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Infectious Diseases Editors' Choice: Top Stories of 2013

Letter to Readers |
December 31, 2013

Infectious Diseases Editors' Choice: Top Stories of 2013

  1. Larry M. Baddour, MD

A perspective on the most important research in the field from the past year

  1. Larry M. Baddour, MD

Dear Readers,

This has been an exciting year for us, with organizational changes that are reflected in our new title: NEJM Journal Watch Infectious Diseases. We remain devoted to providing clinicians with the information they need to give their patients the best care — and, as part of NEJM Group, we are now poised to do that better than ever.

The top infectious diseases stories this year vary considerably, but some common themes are evident. First, novel therapies are important — fecal transplant for recurrent Clostridium difficile infection, dual β-lactam therapy for enterococcal endocarditis, and tenofovir treatment of hepatitis B virus infection with reversal of cirrhosis, for example. Second, the problem of antibiotic resistance is growing, complicating the treatment of many bacterial infections, including gonorrhea. Third, infection-control practices relating to compounding of medicinal agents need to be reevaluated, as was shown by a major outbreak of fungal infections in patients who received contaminated steroid injections. Fourth, the world of infectious diseases continues to expand with newly recognized pathogens, including the Middle East respiratory syndrome coronavirus.

Fungal Meningitis After a Contaminated Epidural Steroid Injection

HBV Treatment Reverses Cirrhosis

Donor Feces for Recurrent Clostridium difficile Infection

Agricultural Antibiotic Use and Antibiotic Resistance

Ampicillin plus Ceftriaxone for Enterococcus faecalis Endocarditis

MERS Coronavirus — An Update

Gonococcal Treatment Failure Due to Cephalosporin Resistance Now in North America

Novel Avian-Origin Influenza A (H7N9) Virus in China

The Human Gut Virome

Can Gloves and Gowns Prevent the Spread of Antibiotic-Resistant Bacteria?

Editor Disclosures at Time of Publication

  • Disclosures for Larry M. Baddour, MD at time of publication Editorial boards UpToDate Leadership positions in professional societies American Heart Association (Chairman, Rheumatic Fever, Endocarditis, Kawasaki Disease Committee)

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