Physician's First Watch Archive

Medical news from NEJM Journal Watch

May 25, 2017

By the Editors

An advisory panel recommended on Wednesday that the FDA approve the breast cancer drug neratinib (to be marketed as Nerlynx), …

By Amy Orciari Herman

Edited by Susan Sadoughi, MD, and Richard Saitz, MD, MPH, FACP, DFASAM

Adjunctive treatment with cannabidiol — a nonhallucinogenic cannabinoid — may reduce seizure frequency in young people with the Dravet syndrome, according to an industry-funded …

By Kelly Young

Edited by Susan Sadoughi, MD, and Richard Saitz, MD, MPH, FACP, DFASAM

The FDA has approved pembrolizumab (Keytruda) to treat patients who have solid tumors with biomarkers known as microsatellite instability-high (MSI-H) or …

May 24, 2017

By Joe Elia

Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM

A Danish cohort study finds that moderate intake of chocolate lowers risks for atrial fibrillation (AF); editorialists in Heart, …

By Amy Orciari Herman

Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM

High-quality chondroitin sulfate is as effective as celecoxib in treating knee osteoarthritis, according to an international trial in the …

By Kristin J. Kelley

Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM

There isn't evidence to warrant restricting the use of gadolinium-based contrast agents …

By the Editors

The World Health Organization has elected Dr. Tedros Adhanom Gheybreysus to be its …

By Amy Orciari Herman

Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM

For patients with uncomplicated cellulitis, adding trimethoprim-sulfamethoxazole (TMP/SMX) to cephalexin may offer no benefit beyond cephalexin alone, a JAMA study finds.

Some 500 patients older than 12 years seen in …

May 23, 2017

By the Editors

Subcutaneous tocilizumab (Actemra) is now approved for adults with giant cell arteritis, the FDA announced …

By Kelly Young

Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD

Older adults with hypertension and hyperlipidemia might not benefit from taking pravastatin for primary prevention of cardiovascular events, according to an open-label study in …

By Joe Elia

Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD

Patients taking long-term opioids for polyneuropathy are at increased risk for numerous complications …

By Amy Orciari Herman

Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD

Older black adults are more likely than white adults to have colorectal cancer diagnosed in the 5 …

By Kelly Young

Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD

The investigational monoclonal antibody benralizumab is associated with reduced oral glucocorticoid use in patients with severe asthma, according to a phase 3, industry-funded …

May 22, 2017

By Kelly Young

Edited by Susan Sadoughi, MD, and André Sofair, MD, MPH

The American Academy of Pediatrics has expanded its recommendation against offering juice to all infants 12 months and under because it offers them no …

By the Editors

Here's a quick look at what the NEJM Journal Watch bloggers are talking about right now:

Insights on Residency Training: Chief resident …

By Kelly Young

Edited by Susan Sadoughi, MD, and André Sofair, MD, MPH

As part of the Choosing Wisely campaign, the American Urological Association has added five more medical treatments …

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