From the publishers of The New England Journal of Medicine

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Spotlight

Primary Care

General Medicine Supporting Image

Ultrasound Plus Mammography for Breast Cancer Screening

Adding ultrasound improved detection but led to more false-positives.

Specialty Care

Dermatology Supporting Image

Melanoma Prognosis Based on Anatomic Site

We don’t know why, but location affects prognosis.

Vitamin D and Infections

  • Dermatology
  • Summary and Comment
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The discovery of vitamin D’s role in host defense points to new therapeutic targets in dermatology.

Kidney Failure After Unidentified Filler Injection

  • Dermatology
  • Summary and Comment
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Three cases of severe complications occurred after injections by an unlicensed operator.

A Few More T Cells and Cytokines to Investigate in Psoriasis

  • Dermatology
  • Summary and Comment
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Th17 cells, known to be linked to autoimmune disorders, were found at elevated levels in psoriatic plaques.

Troponins and Acute Decompensated Heart Failure

In acute decompensated heart failure, as in acute coronary syndromes, troponin elevation portends worse outcome.

Acute Hemorrhagic Stroke: rFVIIa Is Not Effective

The promise shown previously for rFVIIa was not sustained in this trial.

Is CT Plus MRI Better Than CT Alone for Cervical Spine Evaluation?

These findings support the use of MRI in patients with unreliable neurologic exams.

Acute Lung Injury: A Result of How and When We Treat Septic Shock

Delayed goal-directed resuscitation, recent chemotherapy, and delayed antibiotic administration were risk factors for acute lung injury in an observational cohort study.

Pay for Performance: Emergency Medicine Is No Longer Immune

Not all measures are appropriate, but they could have been even worse.

Renal Damage from Oral Sodium Phosphate

Acute phosphate nephropathy is a real concern, even in patients with normal preprocedure renal function.

H. pylori Eradication and Gastric Intestinal Metaplasia

Although histologic scores were not reduced with H. pylori eradication, the cellular phenotype of gastric intestinal metaplasia was changed in many patients.

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