From the publishers of The New England Journal of Medicine

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Spotlight

Primary Care

Women's Health Supporting Image

Should We Add Liver Toxicity to Black Cohosh’s Résumé?

A U.S. Pharmacopeia committee rated the likelihood of black cohosh causing liver damage as "possible."

Specialty Care

Cardiology Supporting Image

Preventing Stroke Recurrence: How Best to Control Hypertension?

In a randomized trial, use of an ARB to lower blood pressure in patients with recent stroke did not improve outcomes.

Translating Hemoglobin A1c into Average Glucose Values

In stable diabetic patients, each percentage point of HbA1c corresponded to about a 29 mg/dL increment in estimated average glucose.

Let Them Eat Nuts (and Popcorn)! Neither Causes Diverticular Complications

No evidence of harm, and possibly even some benefit

Steroid Injections for Trigger Finger

Insulin-dependent diabetes mellitus was the only independent predictor of recurrent symptoms.

Hyperinsulinism in Daughters of Mothers with Polycystic Ovary Syndrome

The authors suggest that hyperinsulinism may be the first and most common abnormality in the daughters of mothers with PCOS.

Which Short-Chain Carbs Are the Villains in IBS?

Researchers challenged IBS patients with dietary fructose, fructans, and glucose.

Frequency of Small-Bowel Injury with Lumiracoxib

Is lumiracoxib less injurious than naproxen plus omeprazole?

Can Recombinant Factor VIIa Control Variceal Hemorrhage?

Researchers looked for benefits in controlling bleeding, preventing rebleeding, and improving survival during the first 5 days of therapy.

Treatment of HIV Infection: Updated Guidelines from the IAS–USA

The panel recommends that HIV-infected patients with CD4 counts <350 cells/mm3 be treated and that therapy be considered in patients with higher CD4 counts.

Pseudomonas aeruginosa Bacteremia

In two retrospective studies, researchers examined the incidence of P. aeruginosa bacteremia and the risk factors associated with this condition.

Reduced Susceptibility to Metronidazole in C. difficile

Nearly one quarter of recent ribotype 001 isolates showed reduced susceptibility to metronidazole.

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