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Breast Cancer: Genomic Analysis Shows 10 Distinct Types — Physician’s First Watch

Medical News |
April 23, 2012

Breast Cancer: Genomic Analysis Shows 10 Distinct Types

Patients may ask about a widely reported, genomics-based investigation that further characterizes breast cancers into specific clinical subgroups. The work appears online in Nature.

Researchers first studied tumor samples from some 1000 patients with breast cancer. Good clinical follow-up data were available for all patients. On the basis of genomic analyses, the tumors fell into 10 distinct clinical subtypes — some carrying a higher mortality risk than others. The researchers then confirmed their findings in a validation set of another 1000 tumors.

The authors say their findings may help to better classify patients' tumors and could aid in examining how the different tumor types respond to various therapies.

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