Statins Associated with Less Cognitive Decline — Physician’s First Watch

Medical News |
July 29, 2008

Statins Associated with Less Cognitive Decline

Elderly people on statins showed a lower rate of cognitive decline than those not taking them, according to a prospective observational study in Neurology.

Researchers followed a population-based cohort over 5 years, examining the participants' medicine cabinets for prescription drug use and measuring their cognitive status annually. The cohort comprised nearly 1700 Mexican American subjects, all over age 60, roughly a quarter of whom took statins at some time during the study.

By the end of the study, those who'd taken statins were about half as likely to have developed either dementia or cognitive impairment without dementia as others in the cohort.

The authors point out that there have been no primary prevention trials of statins for dementia. Writing in Journal Watch Cardiology, Joel M. Gore says that such studies are needed "before statins are routinely deployed to prevent cognitive decline."

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