Meta-Analysis: Vasectomy Likely Does Not Cause Prostate Cancer — Physician’s First Watch

Medical News |
July 18, 2017

Meta-Analysis: Vasectomy Likely Does Not Cause Prostate Cancer

By Amy Orciari Herman

Edited by David G. Fairchild, MD, MPH

A new meta-analysis in JAMA Internal Medicine may help ease patients' concerns about a previously reported link between vasectomy and prostate cancer.

The analysis included over 50 cohort, case-control, or cross-sectional studies comprising nearly 15 million men. Follow-up in the cohort studies ranged from 2 to 24 years.

A small, statistically significant association was observed between vasectomy and any prostate cancer, but when study quality was considered, the association approached the null. For example, analysis of cohort studies with a low risk of bias yielded a 5% increase in risk with vasectomy. There were no associations between vasectomy and incident high-grade, advanced, or fatal prostate cancer.

The researchers calculate that vasectomy is associated with, at most, a 0.6% absolute increase in prostate cancer risk. They conclude that any association "is unlikely to be causal and should not preclude the use of vasectomy as a long-term contraceptive option."

Your Comment

(will not be published)

Filtered HTML

  • Allowed HTML tags: <a> <em> <strong> <cite> <blockquote> <code> <ul> <ol> <li> <dl> <dt> <dd>
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.
Do you have any conflict of interest to disclose?
CAPTCHA
This question is for testing whether you are a human visitor and to prevent automated spam submissions.

Vertical Tabs

* Required

Reader comments are intended to encourage lively discussion of clinical topics with your peers in the medical community. We ask that you keep your remarks to a reasonable length, and we reserve the right to withhold publication of remarks that do not meet this standard.

PRIVACY: We will not use your email address, submitted for a comment, for any other purpose nor sell, rent, or share your e-mail address with any third parties. Please see our Privacy Policy.