Cirrhosis Tied to Stroke Risk — Physician’s First Watch
Cirrhosis Tied to Stroke Risk
By Kelly Young
Cirrhosis is associated with increased risk for stroke in older adults, according to a JAMA Neurology study.
Using administrative claims data, researchers studied 1.6 million Medicare beneficiaries, of whom 1% had cirrhosis. During a mean 4 years' follow-up, 5% of the cohort was hospitalized for stroke.
After adjustment for risk factors and comorbidities, cirrhosis at baseline was associated with elevated risk for any stroke (annual stroke incidence, 2.2% for people with cirrhosis vs. 1.1% for those without). The association was stronger for intracerebral hemorrhage and subarachnoid hemorrhage than for ischemic stroke. Results were similar for patients with alcohol-related and non-alcohol-related cirrhosis.
The authors note that cirrhosis can be accompanied by mixed coagulopathy that could affect hemorrhagic and thrombotic processes.