Cirrhosis Tied to Stroke Risk — Physician’s First Watch

Medical News |
June 6, 2017

Cirrhosis Tied to Stroke Risk

By Kelly Young

Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD

Cirrhosis is associated with increased risk for stroke in older adults, according to a JAMA Neurology study.

Using administrative claims data, researchers studied 1.6 million Medicare beneficiaries, of whom 1% had cirrhosis. During a mean 4 years' follow-up, 5% of the cohort was hospitalized for stroke.

After adjustment for risk factors and comorbidities, cirrhosis at baseline was associated with elevated risk for any stroke (annual stroke incidence, 2.2% for people with cirrhosis vs. 1.1% for those without). The association was stronger for intracerebral hemorrhage and subarachnoid hemorrhage than for ischemic stroke. Results were similar for patients with alcohol-related and non-alcohol-related cirrhosis.

The authors note that cirrhosis can be accompanied by mixed coagulopathy that could affect hemorrhagic and thrombotic processes.

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