Largest U.S. Cluster of VIM-Producing CRE Found in Hospital — Physician’s First Watch

Medical News |
February 26, 2016

Largest U.S. Cluster of VIM-Producing CRE Found in Hospital

By Christine Sadlowski

Edited by André Sofair, MD, MPH, and William E. Chavey, MD, MS

The largest U.S. cluster of colonization with Verona integron-encoded metallo-beta-lactamase–producing Carbapenem-resistant Enterobacteriaceae (VIM-producing CRE) has been identified though active surveillance perirectal cultures at a Kentucky hospital, researchers write in MMWR.

Six patients, including neonates in intensive care, were colonized with four species total but had no clinical symptoms. A source was not found.

Previous VIM-producing CRE clusters have only involved single CRE species. VIM-producing CRE requires prolonged treatment and is more prone to relapses. Risk factors include travel to endemic countries and treatment in healthcare settings or with antimicrobials.

The authors recommend following the strict infection control procedures from the CDC's 2015 CRE toolkit update.

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