Treating Mild Hypertension Might Confer Cardiovascular Benefits — Physician’s First Watch

Medical News |
December 23, 2014

Treating Mild Hypertension Might Confer Cardiovascular Benefits

By Kelly Young

Edited by David G. Fairchild, MD, MPH

Antihypertensive treatment in patients with grade 1 hypertension is associated with reduced cardiovascular risk, according to a meta-analysis in the Annals of Internal Medicine.

Researchers analyzed the results of trials that examined the effects of various antihypertensive regimens in roughly 15,000 patients with grade 1 hypertension (140–159/90–99 mm Hg) and no preexisting cardiovascular disease. The comparison groups either received placebo or less intensive antihypertensive regimens. Over roughly 5 years' follow-up, the mean blood pressure reduction was 3.6/2.4 mm Hg in the treatment groups versus the comparison groups.

Patients in the treatment groups had significantly lower risks for stroke (odds ratio, 0.72), cardiovascular death (OR, 0.75), and all-cause mortality (OR, 0.78). Other outcomes had nonsignificant risk reductions.

The authors say their results "suggest that blood pressure reduction is likely to provide benefit among patients with grade 1 hypertension and that these benefits could be substantial."

Your Comment

(will not be published)

Filtered HTML

  • Allowed HTML tags: <a> <em> <strong> <cite> <blockquote> <code> <ul> <ol> <li> <dl> <dt> <dd>
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.
Do you have any conflict of interest to disclose?
Last load event
Format: 2016-08-28 19:00:11
CAPTCHA
This question is for testing whether you are a human visitor and to prevent automated spam submissions.

Vertical Tabs

* Required

Reader comments are intended to encourage lively discussion of clinical topics with your peers in the medical community. We ask that you keep your remarks to a reasonable length, and we reserve the right to withhold publication of remarks that do not meet this standard.

PRIVACY: We will not use your email address, submitted for a comment, for any other purpose nor sell, rent, or share your e-mail address with any third parties. Please see our Privacy Policy.