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No Increase in VTE after HPV Vaccination — Physician’s First Watch

Medical News |
July 9, 2014

No Increase in VTE after HPV Vaccination

By Christine Sadlowski

Edited by David G. Fairchild, MD, MPH, and Richard Saitz, MD, MPH, FACP, FASAM

The human papillomavirus (HPV) vaccine was not associated with increased risk for venous thromboembolism (VTE) in an analysis of data from Danish national registries, published in a JAMA research letter.

The study included nearly 900 girls and women aged 10 through 44 who developed VTE and received the HPV vaccine. After adjustment for age, the risk for VTE during the 42 post-vaccination days, compared with observations of the same women before and after that period, was not statistically significant.

The authors note that previous reports of a possible association between the vaccine and VTE either came from passive surveillance or were based on only a few vaccinated patients.

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