Higher Serum Vitamin D Linked to Lower Mortality Risk — Physician’s First Watch
Higher Serum Vitamin D Linked to Lower Mortality Risk
By Kelly Young
Edited by David G. Fairchild, MD, MPH
Higher vitamin D levels were associated with reduced mortality risk in a BMJ meta-analysis.
Researchers analyzed the results of eight cohort studies among some 26,000 adults aged 50 to 79 years in the U.S. and Europe. Compared with the highest quintile of serum 25-hydroxyvitamin D concentration, the lowest quintile was associated with increased risk for all-cause mortality (risk ratio, 1.57) and for cardiovascular mortality in people without a history of CVD (RR, 1.41) and in those with a history of CVD (RR, 1.65). There was also increased risk for cancer-related mortality, but only in people who'd previously had cancer (RR, 1.70).
The authors say their findings support the notion that 25(OH)D levels "might be a marker for a poor health status rather than a cause of premature mortality."