Advertisement

CDC Recommends Daily Truvada to Prevent HIV Acquisition in High-Risk Adults — Physician’s First Watch

Medical News |
May 16, 2014

CDC Recommends Daily Truvada to Prevent HIV Acquisition in High-Risk Adults

By Amy Orciari Herman

The CDC now recommends daily treatment with Truvada to lower the risk for HIV acquisition among high-risk adults, including some men who have sex with men (MSM) and injection drug users. The Truvada pill contains 300 mg tenofovir disoproxil fumarate and 200 mg emtricitabine.

Among the groups for whom pre-exposure prophylaxis with Truvada is recommended:

  • MSM not in a monogamous relationship who engage in unprotected anal intercourse

  • Heterosexually active adults who rarely use condoms during sex with high-risk partners of unknown HIV status

  • All adults in an ongoing relationship with an HIV-infected partner

  • Injection drug users who share needles

Individuals must test negative for HIV before beginning Truvada, and they should be assessed every 3 months thereafter. Those who acquire HIV should discontinue the drug.

HIV/ID expert Paul Sax commented: "It is clear that this intervention prevents HIV infection among those who are compliant with the regimen. The key will be targeting those who are at highest risk, a task that will fall on primary care providers."

Reader Comments (3)

ASNA KHAN Physician, Cardiology, India

What about the side effects and whether any relation to CD4 counts?

Henry Onyegbutulem Physician, Endocrinology, Hospital

My concern here is the high chances of developing resistant strains.

Idan Drori, MD Physician

How come the prophylactic medications are nucleoside and nucleotide reverse transcriptase inhibitors (emtricitabine and tenofovir) and not entry inhibitors (enfuvirtide and maraviroc) or integrase inhibitor (raltegravir)?

Your Comment

(will not be published)

Filtered HTML

  • Allowed HTML tags: <a> <em> <strong> <cite> <blockquote> <code> <ul> <ol> <li> <dl> <dt> <dd>
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.
Do you have any conflict of interest to disclose?
CAPTCHA
This question is for testing whether you are a human visitor and to prevent automated spam submissions.
Image CAPTCHA
Enter the characters shown in the image.

Vertical Tabs

* Required

Reader comments are intended to encourage lively discussion of clinical topics with your peers in the medical community. We ask that you keep your remarks to a reasonable length, and we reserve the right to withhold publication of remarks that do not meet this standard.

PRIVACY: We will not use your email address, submitted for a comment, for any other purpose nor sell, rent, or share your e-mail address with any third parties. Please see our Privacy Policy.

Advertisement
Advertisement
Advertisement