Compound in Red Wine, Chocolate Shows No Survival Benefit in the Elderly — Physician’s First Watch
Compound in Red Wine, Chocolate Shows No Survival Benefit in the Elderly
By Amy Orciari Herman
Dietary resveratrol — a polyphenol found in grapes, red wine, and chocolate — is not associated with improved survival in those aged 65 and older, researchers conclude in JAMA Internal Medicine.
Nearly 800 community-dwelling older adults in Tuscany had urinary resveratrol metabolite concentrations measured and then were followed for roughly 9 years. During that time, one third of participants died. In adjusted analyses, higher baseline resveratrol metabolites did not confer a significant reduction in all-cause mortality. In addition, resveratrol was not associated with cardiovascular disease, cancer, or markers of inflammation.
The authors conclude that "resveratrol levels achieved with a Western diet" don't have a "substantial influence" on survival or other health outcomes.