What about the side effects of treatment -and the fact that only 20-30% respond?? I have had people die from rare anemias from the "new" HCV treatments.
Hepatitis C: More Results From Sofosbuvir/Ledipasvir & ABT-450/r Combo Trials — Physician’s First Watch
Hepatitis C: More Results From Sofosbuvir/Ledipasvir & ABT-450/r Combo Trials
By Joe Elia
Further presentations from a London liver conference show that hepatitis C is on the run, but the question is, at what cost?
In studies appearing in the New England Journal of Medicine, a single-pill formulation of sofosbuvir plus ledipasvir (shown in other NEJM studies last week to be roughly 95% effective in cirrhosis-free patients) was equally effective among previously untreated as well as previously treated patients, many with cirrhosis.
Similarly, a regimen centered around the protease inhibitor ABT-450 produced at least a 90% sustained virologic response in previously untreated and previously treated patients with compensated cirrhosis.
Editorialists write that previous medical barriers to hepatitis C treatment "may now largely disappear," but that costs are another barrier. Indeed, back-of-the-envelope calculations show the cost to treat the estimated 3.2 million U.S. cases with a 12-week, $84,000 course of sofosbuvir alone (without ledipasvir) comes to roughly $250 billion.