Advertisement

Real-World HPV Study Finds Vaccine Protects Against Cervical Abnormalities — Physician’s First Watch

Medical News |
March 5, 2014

Real-World HPV Study Finds Vaccine Protects Against Cervical Abnormalities

By Kelly Young

Vaccination with the quadrivalent human papillomavirus (HPV) vaccine was associated with reduced risk for cervical abnormalities in young women presenting for their first cervical screening in Australia. Findings from the case-control study appear in BMJ.

Using population registers, researchers matched nearly 12,000 females with cervical abnormalities to roughly 100,000 controls without abnormalities, and then examined rates of HPV vaccination prior to diagnosis (or control date).

The full, three doses of the vaccine were 46% effective against high-grade cervical abnormalities and 34% effective against other abnormalities. The authors estimate that 125 females would need to be vaccinated with all three doses to prevent one high-grade cervical abnormality and 22 to prevent other cervical abnormalities. The vaccine was slightly less effective at two doses.

Reader Comments (1)

Frank Baudino MD Physician, Family Medicine/General Practice, Salud Para La Gente, Watsonville, CA

I'm totally underwhelmed with these results.

Your Comment

(will not be published)

Filtered HTML

  • Allowed HTML tags: <a> <em> <strong> <cite> <blockquote> <code> <ul> <ol> <li> <dl> <dt> <dd>
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.
Do you have any conflict of interest to disclose?
CAPTCHA
This question is for testing whether you are a human visitor and to prevent automated spam submissions.
Image CAPTCHA
Enter the characters shown in the image.

Vertical Tabs

* Required

Reader comments are intended to encourage lively discussion of clinical topics with your peers in the medical community. We ask that you keep your remarks to a reasonable length, and we reserve the right to withhold publication of remarks that do not meet this standard.

PRIVACY: We will not use your email address, submitted for a comment, for any other purpose nor sell, rent, or share your e-mail address with any third parties. Please see our Privacy Policy.

Advertisement
Advertisement
Advertisement