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Depression Should Officially Be a Risk Factor for Adverse Outcomes After ACS — Physician’s First Watch

Medical News |
February 26, 2014

Depression Should Officially Be a Risk Factor for Adverse Outcomes After ACS

By Kelly Young

The American Heart Association should consider depression to be a risk factor for adverse outcomes following acute coronary syndromes, according to a scientific statement by an AHA committee.

The statement, published in Circulation, included a review of 53 studies assessing prognoses following ACS. The authors acknowledge heterogeneity among the studies, but they conclude that "the preponderance of evidence" points to depression as a risk factor for all-cause mortality, cardiac mortality, and a composite of all-cause mortality and nonfatal cardiac events after ACS.

They write: "There is not yet any strong evidence that treating depression improves survival after ACS; however, worsening depression is associated with worse clinical outcomes, and severe or persistent depression is reason enough to consider more comprehensive evaluation and treatment or referral to a mental health specialist."

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