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Irreproducible Results? Stem-Cell Advance Found Hard to Duplicate — Physician’s First Watch
Irreproducible Results? Stem-Cell Advance Found Hard to Duplicate
By Joe Elia
Temper the stem-cell celebrations. A finding from two recent Nature studies — that stressing mouse cells transformed them to a pluripotent state — has been hard to verify in other laboratories, according to media reports.
The Wall Street Journal notes that at least nine labs have failed to duplicate the results. And one of the coauthors of the Nature studies has been unable to reproduce the results since he left the lab where the original work was done.
The Scientist says it's had no luck contacting Haruko Obokata, who is the first author on both papers. One researcher told the magazine, "If it's really real, people should be able to replicate it." He added, "Some labs, including ours, will continue to try. ... It's still early; we certainly need to give them the benefit of the doubt."