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Acute Kidney Injury Associated with Increased Coronary Risk — Physician’s First Watch

Medical News |
February 7, 2014

Acute Kidney Injury Associated with Increased Coronary Risk

By Kelly Young

Acute kidney injury (AKI) requiring dialysis may confer as much excess cardiovascular risk as diabetes, suggests a study in the Journal of the American Society of Nephrology.

Nearly 4900 patients in Taiwan who were hospitalized with AKI that required dialysis, recovered from AKI, and survived beyond 30 days postdischarge were matched to 4900 hospitalized patients who did not have AKI or a coronary event. After a mean follow-up of about 3 years, the AKI group had a higher rate of coronary events than the control group (19.8 vs. 10.3 per 1000 patient-years). All-cause mortality following discharge was also higher in the AKI group (178.6 vs. 96.4 per 1000 patient-years).

Editorialists caution that these findings, based on administrative data, may be subject to confounding and misclassification.

Reader Comments (2)

manuel Physician, Surgery, General, national university of trujillo

may I read it¡

Tom Hight Physician, Internal Medicine

Is AKI more prevalent when there is renal artery atherosclerosis? Probably is. Perhaps we should be screening post-AKI patients with coronary artery calcium scoring +/or renal artery calcium scoring. Although many are being screened w/ renal artery ultrasound to R/O hemodynamically significant disease, I think we should also be looking for non-hemodynamically significant disease in renal arteries of patients who've survived AKI .

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