Adrenal "Incidentalomas" May Confer Cardiovascular Risk — Physician’s First Watch

Medical News |
January 29, 2014

Adrenal "Incidentalomas" May Confer Cardiovascular Risk

By Joe Elia

Adrenal masses found in the course of abdominal imaging seem associated with an increased risk for cardiovascular disease, according to a Lancet Diabetes & Endocrinology article.

In a retrospective study, 198 patients with adrenal incidentalomas were followed over an average of 8 years. The patients were classified according to their cortisol levels after dexamethasone suppression: stable nonsecretors, intermediate (50 to 138 nmol/L) and subclinical Cushing's (above 138 nmol/L) secretors, and those whose cortisol levels increased over time. Roughly two thirds of the patients were nonsecretors.

The incidence of cardiovascular events was significantly higher in the intermediate or subclinical Cushing's group than in stable nonsecretors (17% vs. 7%); it was even higher (28%) among those whose cortisol levels increased. Cardiovascular mortality rates were also adversely affected, but cancer mortality was similar across the groups.

Commentators say the findings show the importance of follow-up and clinical monitoring of cardiovascular risk in these patients.

Reader Comments (1)

Henry Wilde Physician, Infectious Disease, university

Interesting. I just had an adrenal adenoma found as a coincidental finding about 2 cm. No symtoms. Feel fine. Had a kidney stone thi swas why CT done

Your Comment

(will not be published)

Filtered HTML

  • Allowed HTML tags: <a> <em> <strong> <cite> <blockquote> <code> <ul> <ol> <li> <dl> <dt> <dd>
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.
Do you have any conflict of interest to disclose?
This question is for testing whether you are a human visitor and to prevent automated spam submissions.

Vertical Tabs

* Required

Reader comments are intended to encourage lively discussion of clinical topics with your peers in the medical community. We ask that you keep your remarks to a reasonable length, and we reserve the right to withhold publication of remarks that do not meet this standard.

PRIVACY: We will not use your email address, submitted for a comment, for any other purpose nor sell, rent, or share your e-mail address with any third parties. Please see our Privacy Policy.