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Circulating Endothelial Cells as Biomarkers for Predicting MI? — Physician’s First Watch
Circulating Endothelial Cells as Biomarkers for Predicting MI?
By Joe Elia
Patients may ask about a study suggesting that the presence of endothelial cells in the circulation might be an additional tool for predicting myocardial infarction. Findings from the small study appear in Physical Biology.
Researchers, adopting an assay they developed to enumerate circulating tumor cells, used cell-surface antigens to identify endothelial cells in blood samples. Some 80 patients being evaluated for (and subsequently confirmed to have suffered) an MI were compared with 6 patients undergoing carotid endarterectomy and 25 healthy controls.
Circulating endothelial cells were significantly more common among the MI patients than among either the healthy controls or those who'd undergone vascular surgery.