In COPD, Beta-Blockers Lower Mortality After MI — Physician’s First Watch

Medical News |
November 26, 2013

In COPD, Beta-Blockers Lower Mortality After MI

By Joe Elia

Beta-blocker use, sometimes limited in patients with chronic obstructive pulmonary disease because of worry over inducing bronchospasm, offers a survival advantage after myocardial infarction in such patients, a BMJ study shows.

Researchers used U.K. national databases to examine outcomes in 1063 patients with COPD who were hospitalized after sustaining a first MI.

Patients prescribed beta-blockers during their hospital stay showed a mortality hazard ratio of 0.50 relative to those not prescribed them. Patients already on the drugs before the MI also showed a significant survival advantage (HR, 0.59).

The authors note that only about one third of the patients were prescribed a beta-blocker during their hospitalization, adding that use of the drugs in the U.S. has increased in recent years and now exceeds 90% of such patients.

Reader Comments (3)

namita tiwari Resident, Surgery, General

This is a good observational study. I have seen the use of bb on patients with COPD but who had high BP and tachycardia and the use of BB (although low does) significantly helped these patients and there was no complication of bronchospasm noticed.
However, i think it is dose related.

noel Kayo Resident, Internal Medicine, University cardiovascular research

This is a very good observational study. We hope to see the same with post MI cocaine.

Miguel Gambetta Physician, Cardiology

Dose prescribed? Was it "low"? Whatever dose, it was good for these patients.

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