People with HIV Have a 10-Fold Higher Risk for Invasive Meningococcal Disease — Physician’s First Watch
People with HIV Have a 10-Fold Higher Risk for Invasive Meningococcal Disease
By Joe Elia
Being seropositive for HIV in New York City puts a person at a roughly 10-fold greater risk for invasive meningococcal disease, a study in the Annals of Internal Medicine finds.
Researchers examined city registry data from 2000 to 2011. The incidence rates of invasive meningococcal disease were 0.34 per 100,000 overall and 3.4 per 100,000 among those with HIV. Among seropositives, those with CD4+ counts under 200 were five times more likely to have invasive meningococcal disease than those with higher counts.
The CDC does not include HIV-seropositive adults as a risk group warranting meningococcal vaccination; the authors recommend that the agency revise its position.
Paul Sax, an ID specialist forNEJM Journal Watch, commented: "These data certainly suggest that people with HIV are at increased risk for this potentially life-threatening complication, and raise the question of whether meningococcal immunization should be considered standard-of-care for HIV-infected adults as well as adolescents."