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More Evidence for Link Between Omega-3 Fatty Acids and Prostate Cancer — Physician’s First Watch

Medical News |
July 11, 2013

More Evidence for Link Between Omega-3 Fatty Acids and Prostate Cancer

By Amy Orciari Herman

A new study confirms a previously reported association between high serum concentrations of omega-3 fatty acids and increased prostate cancer risk, researchers report in the Journal of the National Cancer Institute.

In an analysis nested within a cancer prevention trial, some 800 men with prostate cancer were matched by age and race to a subcohort of 1400 men. Compared with men in the lowest quartile of serum long-chain omega-3 fatty acid concentration, those in the highest quartile had a significant, 40% increased risk for low-grade prostate cancer or total prostate cancer; the risk for high-grade disease was increased by 70%, a finding of borderline statistical significance.

The authors say their study, when considered alongside previous research, "strongly suggests" that long-chain omega-3 polyunsaturated fatty acids "do play a role in enhancing prostate tumorigenesis." They conclude that recommendations to increase omega-3 consumption "should consider its potential risks."

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