Editor Profile

Barbara Geller, MD

Associate Editor

About the NEJM Journal Watch Psychiatry Board

Barbara Geller, MD, is Professor Emerita of Psychiatry at Washington University in St. Louis. She is internationally recognized for research into pediatric bipolar disorders and was principal investigator on multiple NIMH-funded grants. Among her awards were the Cummings Special Research Award from the American Academy of Child and Adolescent Psychiatry and the Exemplary Psychiatrist Award from the National Alliance for the Mentally Ill. Dr. Geller served on numerous federal advisory committees and published more than 130 articles on childhood manic-depressive disorders. She has been writing for NEJM Journal Watch Psychiatry since 1997, specializing in articles on child psychiatry and neuroscience.

Dr. Geller has no disclosures.

  • August 24, 2016

    Does Immune-Based Therapy Work for PANDAS?

    1. Barbara Geller, MD

    Although antibodies that cross-react with basal ganglia tissue occur in PANDAS, this randomized trial of treatment with immunoglobulin was negative.

  • August 17, 2016

    A “Recreational Genetics” Perspective on Depression Genes

    1. Barbara Geller, MD

    Based partly on data from the commercial company 23andMe, researchers identified 17 genetic polymorphisms related to depression, many of which are implicated in brain development.

  • August 4, 2016

    Good Start, Good Brain

    1. Barbara Geller, MD

    Across the lifespan, trajectories of brain size and cognition followed parallel pathways, and the highest trajectories were associated with greater birthweight and better parental education.

  • July 25, 2016

    A Likely Cause of Lithium-Associated Parkinsonian Tremor

    1. Barbara Geller, MD

    Lithium increases iron in the substantia nigra, as does Parkinson disease, via pathways that lower amyloid and phosphorylated tau levels and impair cellular iron efflux.

  • July 18, 2016

    Cycloserine Augmentation for Children with Obsessive-Compulsive Disorder?

    1. Barbara Geller, MD

    Outcomes did not improve when cognitive-behavioral therapy was augmented with D-cycloserine, regardless of whether children were also taking antidepressants.

  • July 8, 2016

    Like Father, Like Son

    1. Barbara Geller, MD

    Both stressed male mice and their male offspring exhibited impaired behavior and hippocampal and spermatic epigenetic changes; some of these were reversed by environmental enrichment.