Premenstrual Dysphoric Disorder: An OC Offers Some Relief
Psychiatry
General Medicine
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Premenstrual dysphoric disorder (PMDD) disrupts the lives of 3% to 5% of women. The biologic process is unknown, but combined oral contraceptives (OCs) have been . . .
By Sandra Ann Carson, MD
January 25, 2006
Hypertension Linked to Cognitive Decline and Dementia
Psychiatry
General Medicine
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This review examines published reports from the last 15 years about blood pressure (BP) and the development of dementia/cognitive decline. The authors consider the effects . . .
By David A. Drachman, MD
January 25, 2006
Do Neuropsychiatric Symptoms Differ Between AD and Vascular Dementia?
Psychiatry
General Medicine
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Given that the neuropsychiatric symptoms of dementia play an important role in patient disability, caregiver distress, and need for institutionalization, this class of symptoms requires . . .
By David A. Wolk, MD
January 25, 2006
Sibutramine Plus Lifestyle Modification Is Effective for Weight Loss
Psychiatry
General Medicine
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We always recommend lifestyle modification when we prescribe weight-loss medications, but the intensity, and therefore the benefit, of such modification is usually minimal. In this . . .
By Thomas L. Schwenk, MD
January 12, 2006
Rimonabant for Weight Loss: Another Encouraging Study
Psychiatry
General Medicine
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The selective cannabinoid-receptor blocker rimonabant produces sustained weight loss and improvement in several metabolic parameters (Lancet 2005; 365:1389). To further explore the effects of . . .
By Anthony L. Komaroff, MD
January 12, 2006
Teasing Apart Apathy and Depression in AD
Psychiatry
General Medicine
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Patients with dementia exhibit symptoms of apathy, depression, and anxiety that can be debilitating. The treatments of these symptoms differ, making careful diagnosis necessary. Estimates . . .
By Melissa Frumin, MD, MS
December 21, 2005
Rates of Decline and Survival in FTLD and Its Subtypes
Psychiatry
General Medicine
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To compare rates of progression and survival in frontotemporal lobar degenerations (FTLD, a category that includes frontotemporal dementia and the progressive aphasias) and in Alzheimer . . .
By David Knopman, MD
December 21, 2005
Which Smells Best Predict Dementia?
Psychiatry
General Medicine
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At long last it is generally acknowledged, on the basis of pathologic and clinical investigations, that one of the earliest symptoms of Alzheimer disease (AD) . . .
By Christopher Hawkes, MD
December 7, 2005
Suicidal Mother, Suicidal Child?
Psychiatry
General Medicine
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Although suicidality appears to run in families, most research has focused on patients receiving treatment for suicidality; thus, familial associations might apply to only the . . .
By Nada L. Stotland, MD, MPH
December 7, 2005
Update on Insomnia Treatment
Psychiatry
General Medicine
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Insomnia and sleep deprivation are receiving more recognition for their potential roles in the precipitation and maintenance of medical and psychiatric illnesses. This feature by . . .
By John W. Winkelman, MD, PhD
December 7, 2005