Which ART Regimen Is Best After Receipt of Single-Dose Nevirapine?
HIV/AIDS Clinical Care
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Preliminary results from the OCTANE trial suggest that lopinavir/r-based regimens are more effective than nevirapine-based ones, particularly when ART is initiated shortly after exposure to single-dose nevirapine.
By Catherine Tomeo Ryan
November 17, 2008
Concurrent ART/TB Treatment Finally Proven to Be Beneficial
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Giving ART while TB treatment was still ongoing dramatically improved survival among HIV/TB-coinfected patients in a large clinical trial in South Africa.
By ACC Editors
September 29, 2008
HIV Vaccine Trial Canceled
HIV/AIDS Clinical Care
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NIAID will not conduct the HIV vaccine study known as PAVE 100. Instead, officials are considering a smaller, more focused trial.
By Dan H. Barouch, MD, PhD
August 4, 2008
FTC + Atazanavir + ddI Deemed Inferior to AZT/3TC + Efavirenz
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Patients receiving FTC + atazanavir + ddI in an ongoing ACTG trial are being switched to other regimens but will continue to be followed.
Abacavir/3TC vs. Tenofovir/FTC: Interim Results from ACTG 5202
HIV/AIDS Clinical Care
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An interim analysis from ACTG 5202 suggests that abacavir/3TC is not as effective as tenofovir/FTC in reducing viral load among treatment-naive patients with high viral loads (100,000 or more copies/mL) at baseline.
HIV-1 Vaccine Might Increase Infection Risk in Certain Subgroups
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The HIV-1 vaccine used in the STEP trial has already been shown to be ineffective, but might it actually cause harm?
HIV-1 Vaccine Candidate Ineffective
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The vaccine used in the international STEP trial failed to prevent HIV-1 infection and also did not reduce viral load in those who became infected.
By Dan H. Barouch, MD, PhD
October 1, 2007
Anti-HIV Microbicide Trials Halted
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Preliminary results indicate that the risk for HIV infection is higher among women using cellulose sulfate than among those using placebo.
By ACC Editors
February 12, 2007
Circumcision Greatly Reduces Risk for HIV Infection
HIV/AIDS Clinical Care
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Adult male circumcision halved the risk for HIV transmission in an interim analysis of two randomized, controlled studies.
APTIMA Assay Approved for HIV Testing
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For the first time, the FDA has recognized a nucleic-acid test as a tool for diagnosing HIV infection.
By Rochelle P. Walensky, MD, MPH
October 30, 2006