Early ART Initiation Improves Survival in Resource-Limited Settings
HIV/AIDS Clinical Care
Meeting Report
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New findings from Haiti (described at IAS 2009) support starting ART when CD4 counts fall below 350 cells/mm3 — the same threshold that is recommended in resource-rich settings.
Report from the 5th IAS Conference on HIV Pathogenesis, Treatment and Prevention
HIV/AIDS Clinical Care
Meeting Report
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Our physician-editors detail the most important findings from this year's meeting
By ACC Editors
August 31, 2009
Report from the XVIII International HIV Drug Resistance Workshop
HIV/AIDS Clinical Care
Meeting Report
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An expert's take on the most clinically relevant reports from this year's resistance meeting
By Daniel R. Kuritzkes, MD
August 24, 2009
SWITCHMRK: An Avoidable Raltegravir Disaster
HIV/AIDS Clinical Care
Meeting Report
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Somewhat predictably, treatment-experienced patients on stable regimens who switched from lopinavir/r to raltegravir did not fare as well as those who remained on lopinavir/r.
Timing of ART Initiation — Still No Definitive Answers
HIV/AIDS Clinical Care
Meeting Report
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Data from two observational studies presented at CROI 2009 are informative but not conclusive. However, both studies point to starting therapy at least before the CD4 count falls below 350 cells/mm3 .
No Clinical Benefit from Adding IL-2 to ART
HIV/AIDS Clinical Care
Meeting Report
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In two large trials presented at CROI 2009, CD4-cell increases were greater with IL-2 and ART together than with ART alone, but these increases did not lead to reductions in morbidity or mortality.
First (Sort of) Positive Anti-HIV Microbicide Trial
HIV/AIDS Clinical Care
Meeting Report
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Promising results from HPTN 035, a phase II trial of two microbicides, were reported at the 2009 Retrovirus Conference.
Investigational Pharmacologic Boosters
HIV/AIDS Clinical Care
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Two promising alternatives to ritonavir were described at this years Retrovirus Conference.
Report from the 16th Conference on Retroviruses and Opportunistic Infections
HIV/AIDS Clinical Care
Meeting Report
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Our physician-editors weigh in on the most clinically relevant findings from the meeting.
Lopinavir/r Is Superior to Nevirapine in Women Who Previously Received Single-Dose Nevirapine
HIV/AIDS Clinical Care
Meeting Report
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In a large African trial described at CROI 2009, rates of both virologic failure and drug discontinuation were lower with lopinavir/r-based regimens than with nevirapine-based ones.