Report from the 19th Conference on Retroviruses and Opportunistic Infections
HIV/AIDS Clinical Care
Meeting Report
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Our physician-editors highlight the most clinically relevant findings from the 2012 meeting in Seattle.
Late Diagnosis and Delayed Entry into Care Continue to Limit the Benefits of ART
HIV/AIDS Clinical Care
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CROI 2012 highlighted the need for stronger efforts in screening, treatment initiation, and retention in care.
Quad Pill Poised to Become the Next One-Pill, Once-Daily Treatment for HIV
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The single-tablet regimen — containing tenofovir, FTC, elvitegravir, and cobicistat — proved both safe and effective in two phase III trials presented at CROI 2012.
Promising Data from the Antiretroviral Pipeline
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CROI 2012 featured 96-week data on dolutegravir and dose-ranging data for the tenofovir prodrug GS-7340.
Adverse Effects of Currently Prescribed Antiretrovirals
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Exploration of metabolic, renal, and cardiovascular effects continued at CROI 2012.
High Adherence Critical to the Success of PrEP
HIV/AIDS Clinical Care
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Data presented at CROI 2012 explain the reason for the lack of PrEP efficacy in the FEM-PrEP trial.
Triple-Drug HCV Therapy for HIV-Coinfected Patients?
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In studies presented at CROI 2012, triple-drug therapy led to more side effects and drug interactions than standard regimens — but also had a dramatically higher success rate.
First Steps Toward a Cure for HIV?
HIV/AIDS Clinical Care
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Some promising data emerged at CROI 2012, but the road ahead is long.
Zoster Vaccine Safe and Immunogenic in HIV-Infected Patients
HIV/AIDS Clinical Care
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CROI 2012 featured results from the first clinical trial of this vaccine in the HIV-infected population.
CPE Scores Fail to Predict Neuropsychiatric Test Performance
HIV/AIDS Clinical Care
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An antiretroviral's CNS penetration effectiveness score should not be part of clinical decision making, according to data presented at IAS 2011.