More from HPTN 052
HIV/AIDS Clinical Care
Meeting Report
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Initiation of antiretroviral therapy in HIV-infected adults at CD4 counts >350 cells/mm3 significantly reduced the incidence of clinical events and is cost-effective, according to two analyses presented at AIDS 2012.
Cobicistat Noninferior to Ritonavir in Boosted PI–Based Regimen
HIV/AIDS Clinical Care
Meeting Report
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Cobicistat proved as safe and effective as ritonavir in a study presented at AIDS 2012.
HIV Cure Research Takes Center Stage
HIV/AIDS Clinical Care
Meeting Report
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Researchers at AIDS 2012 reported that two patients had clearance of HIV reservoirs following allogeneic stem cell transplant — a tantalizing finding that raises new questions for cure research.
Dolutegravir Noninferior to Raltegravir in Treatment-Naive HIV-Infected Patients
HIV/AIDS Clinical Care
Meeting Report
Free Article
A 48-week analysis presented at AIDS 2012 showed virologic suppression rates of 88% for dolutegravir and 85% for raltegravir.
Switching PI-Based ART to a Single-Tablet Regimen — Safe and Effective
HIV/AIDS Clinical Care
Meeting Report
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Switching to tenofovir/FTC/rilpivirine from a boosted protease inhibitor–based regimen worked well, according to data presented at AIDS 2012.
Caution About Two-Drug Regimens Containing Maraviroc plus a Boosted PI
HIV/AIDS Clinical Care
Meeting Report
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In two small studies presented at AIDS 2012, suboptimal treatment responses were seen with regimens consisting of maraviroc plus boosted atazanavir or boosted darunavir.
INH for Prevention of TB — Still the Standard, But For How Long?
HIV/AIDS Clinical Care
Meeting Report
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Data presented at AIDS 2012 demonstrated the efficacy of isoniazid among patients on ART but also highlighted the potential of weekly INH plus rifapentine.
Raltegravir-Based ART in HIV-Related TB
HIV/AIDS Clinical Care
Meeting Report
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A small comparative trial presented at AIDS 2012 demonstrated similar virologic efficacy for efavirenz, standard-dose raltegravir, and double-dose raltegravir.
Sutezolid, a Potential New Weapon Against TB
HIV/AIDS Clinical Care
Meeting Report
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Sutezolid was active against TB in a small 14-day trial presented at AIDS 2012, but more data are needed before we can know the true potential of this drug.
Report from the 2012 International Workshop on HIV & Hepatitis Virus Drug Resistance and Curative Strategies
HIV/AIDS Clinical Care
Meeting Report
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An expert's take on the most clinically relevant reports from this year's resistance meeting
By Daniel R. Kuritzkes, MD
July 9, 2012