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Stroke: Archives

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Items 426-450 of 712 are shown

Carotid Stenting vs. Endarterectomy: Longer-Term Outcomes

Among patients without periprocedural complications, adverse outcomes at ≥2 years did not differ for stenting and endarterectomy.

  • By Allan S. Brett, MD
  • October 9, 2008
  • Covering:
    • Eckstein H-H et al., Lancet Neurol 2008 Oct; 7:893
    • Mas J-L et al., Lancet Neurol 2008 Oct; 7:885

Cigarette Smoking and Stroke Risk in Young Women

Stroke risk was substantially higher in current smokers than in never smokers or former smokers and increased sharply with number of cigarettes smoked daily.

Antipsychotics Increase Risk for Stroke in Elders

The presence of dementia worsens the risk.

  • By Peter Roy-Byrne, MD
  • September 29, 2008
  • Covering:
    • Douglas IJ and Smeeth L., BMJ 2008 Aug 28; 337:a1227

Extending the Time Frame for Alteplase: The ECASS III Trial

In patients with acute ischemic stroke, alteplase may be effective up to 4.5 hours after symptom onset.

  • By Harlan M. Krumholz, MD, SM
  • September 24, 2008
  • Covering:
    • Hacke W et al. for the ECASS Investigators., N Engl J Med 2008 Sep 25; 359:1317

Thrombolysis for Stroke Within 4.5 Hours Is Safe and Effective

But still, the sooner treatment is administered, the better!

  • By J. Stephen Bohan, MD, MS, FACP, FACEP
  • September 24, 2008
  • Covering:
    • Hacke W et al. for the ECASS Investigators., N Engl J Med 2008 Sep 25; 359:1317
    • Lyden P., N Engl J Med 2008 Sep 25; 359:1393

Transcranial Color Doppler and Outcome Prediction in Reversible Cerebral Vasoconstriction Syndrome

A first look at what transcranial color Doppler can tell us about risk for poor outcomes in this group of disorders

  • By Farzaneh A. Sorond, MD, PhD
  • September 23, 2008
  • Covering:
    • Chen S-P et al., Ann Neurol 2008 Jun; 63:751

TPA Treatment for Acute Stroke: Legally Risky?

Not treating seems to be riskiest.

Aspirin Does Not Affect Cognitive Function in People at Moderate CV Risk

Results of a double-blind randomized trial in middle-aged and older patients indicate no effect of long-term low-dose aspirin use on cognitive function.

Telmisartan in ACE-Inhibitor–Intolerant Patients: A Disappointment

In a placebo-controlled trial, researchers found an unexpectedly low, statistically nonsignificant reduction in clinical outcomes.

  • By Beat J. Meyer, MD
  • September 17, 2008
  • Covering:
    • The TRANSCEND Investigators., Lancet 2008 August 31

Good Outcomes for Thrombolysis at 3.0 to 4.5 Hours After Stroke

In a large registry study, rates of mortality, symptomatic intracerebral hemorrhage, and independence at 3 months were similar between patients treated with alteplase within 3.0 hours and patients treated at 3.0 to 4.5 hours after ischemic stroke onset.

  • By Daniel J. Pallin, MD, MPH
  • September 15, 2008
  • Covering:
    • Wahlgren N et al., Lancet 2008 Sep 15

Antipsychotic Medication Increases Stroke Risk

The effects were more pronounced in patients who took atypical antipsychotics and in patients with dementia.

Exposure to Antipsychotics and Risk for Stroke

Use of antipsychotics, especially atypical drugs, raises risk for stroke, and this risk is higher in patients with dementia than in those without.

Clinical Implications of Intraventricular Hemorrhage

Intracerebral hemorrhage volume was linked to presence of intraventricular hemorrhage in this retrospective study.

  • By Kevin Sheth, MD
  • September 9, 2008
  • Covering:
    • Hallevi H et al., Neurology 2008 Mar 11; 70:848

Aspirin/Dipyridamole vs. Clopidogrel to Prevent Recurrent Stroke: A Toss-Up?

Aspirin/dipyridamole and clopidogrel were similarly effective.

  • By Allan S. Brett, MD
  • September 4, 2008
  • Covering:
    • Sacco RL et al., N Engl J Med 2008 Aug 27
    • Kent DM and Thaler DE., N Engl J Med 2008 Aug 27

Telmisartan to Prevent Recurrent Stroke — No Benefit

The rate of recurrent stroke was not significantly different in the telmisartan and placebo groups.

  • By Allan S. Brett, MD
  • September 4, 2008
  • Covering:
    • Yusuf S et al., N Engl J Med 2008 Aug 27

Preventing Stroke Recurrence: How Best to Control Hypertension?

In a randomized trial, use of an ARB to lower blood pressure in patients with recent stroke did not improve outcomes.

Preventing Stroke Recurrence: Which Antiplatelet Strategy Is Best?

In a randomized trial, aspirin plus extended-release dipyridamole showed similar efficacy compared with clopidogrel, although clopidogrel showed a very slight safety advantage.

No Role for Folic Acid or B Vitamins in Lowering Cardiovascular Risk

Another randomized trial fails to show a positive effect of folic acid or B-vitamin supplementation on secondary prevention of CVD events.

Telemedicine for Stroke Patients

Telemedicine consultation with a stroke-certified neurologist might increase appropriate use of thrombolytic agents in stroke patients.

Homocysteine-Lowering Therapy: Another Negative Study

No benefits were found with folic acid, vitamin B12, or vitamin B6 supplementation.

  • By Allan S. Brett, MD
  • August 19, 2008
  • Covering:
    • Ebbing M et al., JAMA 2008 Aug 20; 300:795

Anterior Cerebral Artery Territory Infarction

A description of findings in a Korean cohort

  • By Louis R. Caplan, MD
  • August 19, 2008
  • Covering:
    • Kang SY and Kim JS., Neurology 2008 Jun 10; 70:2386

Generalist vs. Neurologist Care in Acute Ischemic Stroke: Does It Matter?

According to a recent study — no

Gastrointestinal Bleeding Is Associated with Poor Outcomes in Ischemic Stroke Patients

Ischemic stroke patients who have GIB have a higher short-term mortality rate and poorer prognosis than those who do not bleed.

NSAIDs, Cyclooxygenase-2 Inhibitors, and the Risk for Stroke

Findings from an observational study further demonstrate the hazards of rofecoxib and valdecoxib but provide reassurance about currently marketed agents.

  • By Joel M. Gore, MD
  • July 23, 2008
  • Covering:
    • Roumie CL et al., Stroke 2008 Jul; 39:2037

Discriminating Among Congenital Stroke Syndromes

A critical look at MRI data on congenital stroke syndromes refines our concepts of these conditions and highlights the potential importance of periventricular venous infarction.

  • By James Carroll, MD
  • July 22, 2008
  • Covering:
    • Kirton A et al., Ann Neurol 2008 Apr; 63:436
Items 426-450 of 712 are shown

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