Brain CT Findings Enhance Prediction of Stroke After TIA
Neurology
Summary and Comment
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CT findings honed the predictive ability of the ABCD score in an Italian cohort.
By Samir H. Shah, MD, and Bruce Ovbiagele, MD
April 29, 2008
Covering:
Sciolla R and Melis F., Stroke 2008 Feb; 39:297
Prasugrel vs. Clopidogrel, Continued . . .
Cardiology
Summary and Comment
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A subanalysis of TRITON-TIMI 38 suggests that prasugrel lowers stent thrombosis rates in high-risk ACS patients.
By Beat J. Meyer, MD
April 23, 2008
Covering:
Wiviott SD et al. for the TRITON-TIMI 38 Investigators., Lancet 2008 Apr 19; 371:1353
Ajani AE and Lefkovits J., Lancet 2008 Apr 19; 371:1315
Warfarin Increases Delayed Bleeding After Skin Surgery
Dermatology
Summary and Comment
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But there is no need to stop warfarin if careful management is employed.
By George J. Hruza, MD
April 18, 2008
Covering:
Blasdale C and Lawrence CM., Br J Dermatol 2008 Mar; 158:522
An ACE Inhibitor, an ARB, or Both for Patients at High Vascular Risk?
General Medicine
Summary and Comment
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An ARB was as efficacious as an ACE inhibitor, but combination therapy failed to show any advantages.
By Jamaluddin Moloo, MD, MPH
April 17, 2008
Covering:
Yusuf S et al. for the ONTARGET Investigators., N Engl J Med 2008 Apr 10; 358:1547
Ablation Therapy for Atrial Tachycardias: Some Answers, More Questions
Cardiology
Summary and Comment
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A meta-analysis of four randomized comparison trials suggests that ablation may have the edge over drug treatment — but also highlights the paucity of evidence.
Carotid Stenting vs. Endarterectomy — Long-Term Results
General Medicine
Summary and Comment
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At 3 years, outcomes were similar for patients at high surgical risk.
By Allan S. Brett, MD
April 9, 2008
Covering:
Gurm HS et al., N Engl J Med 2008 Apr 10; 358:1572
Is Carotid Plaque a Predictor of Vascular Events?
Cardiology
Summary and Comment
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In an observational study, a simple, noninvasive marker of subclinical atherosclerosis added predictive power to the Framingham Risk Score.
By Joel M. Gore, MD
April 9, 2008
Covering:
Rundek T et al., Neurology 2008 Apr 1; 70:1200
Are Angiotensin-Receptor Blockers Effective Alternatives to ACE Inhibitors?
Cardiology
Summary and Comment
Free
The angiotensin-receptor blocker telmisartan was shown to be as beneficial as the ACE inhibitor ramipril in preventing vascular events in high-risk patients.
By Joel M. Gore, MD
March 31, 2008
Covering:
Yusuf S et al. for the ONTARGET Investigators., N Engl J Med 2008 Apr 10; 358:1547
McMurray JJV., N Engl J Med 2008 Apr 10; 358:1615
Youre Never Too Old to Start Treatment for Hypertension
Cardiology
Summary and Comment
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Findings from a randomized trial suggest that antihypertensive therapy lowers risk not only for stroke, but also for death from any cause.
By JoAnne M. Foody, MD
March 31, 2008
Covering:
Beckett NS et al. for the HYVET Study Group., N Engl J Med 2008 May 1; 358
Closure of Patent Foramen Ovale for Migraine Relief: A Study Headache
Cardiology
Summary and Comment
Free
The final results from the MIST trial are disappointing.
By Howard C. Herrmann, MD
March 26, 2008
Covering:
Carroll JD., Circulation 2008 Mar 18; 117:1358
Dowson A et al., Circulation 2008 Mar 18; 117:1397