Adolescent Outcomes After Pelvic Inflammatory Disease
Adolescents were more likely than adults to have recurrent sexually transmitted infections, to be pregnant at follow-up, and to have a recurrence sooner.
Interim CDC Guidance on Pre-Exposure Prophylaxis for HIV Prevention in MSM
HIV/AIDS Clinical Care Clinical Practice Guideline Watch
Free
In the wake of the iPrEx study, the CDC offers some general guiding principles for the implementation of pre-exposure prophylaxis.
By Raphael J. Landovitz, MD, MSc
February 14, 2011
Covering:
Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2011 Jan 28; 60:65
Male Circumcision for Preventing Transmission of Human Papillomavirus to Women
Women's Health Summary and Comment
In Ugandan trials, adult male circumcision was associated with a 28% reduction in prevalence of high-risk HPV in female partners.
By Anna Wald, MD, MPH
February 10, 2011
Covering:
Wawer MJ et al., Lancet 2011 Jan 15; 377:209
Giuliano AR et al., Lancet 2011 Jan 15; 377:183
HIV and Stroke
Infectious Diseases Summary and Comment
The proportion of hospitalized stroke patients who are HIV-infected is increasing; multiple reasons are likely.
By Rajesh T. Gandhi, MD
February 9, 2011
Covering:
Ovbiagele B and Nath A., Neurology 2011 Feb 1; 76:444
HPV Vaccine Prevents Genital Warts in Men
General Medicine Summary and Comment
Its efficacy against human papillomavirus–related malignancies in men is presumed but not proven yet.
By Abigail Zuger, MD
February 8, 2011
Covering:
Giuliano AR et al., N Engl J Med 2011 Feb 3; 364:401
Male Circumcision Helps Prevent High-Risk HPV Infection in Female Sexual Partners
General Medicine Summary and Comment
The prevalence and incidence of human papillomavirus infections were lower among women whose male partners were circumcised.
By Bruce Soloway, MD
February 3, 2011
Covering:
Wawer MJ et al., Lancet 2011 Jan 15; 377:209
Human Papillomavirus Vaccine Approved to Prevent Anal Cancer
Infectious Diseases Vaccine Watch
Free
The FDA has approved Gardasil for preventing anal cancer in people aged 9 through 26.
New HIV Guidelines Change the Schedule for CD4 Monitoring
HIV/AIDS Clinical Care Clinical Practice Guideline Watch
Once a year may be enough in stable patients, according to the DHHS.
By Abigail Zuger, MD
January 24, 2011
Covering:
Department of Health and Human Services Panel on Antiretroviral Guidelines for Adults and Adolescents.,
Comparing Rapid HIV Antibody Tests in a Clinical Setting
All six rapid HIV tests included in this evaluation had high sensitivity and specificity, with no significant differences among them.
By Charles B. Hicks, MD
January 24, 2011
Covering:
Delaney KP et al., Clin Infect Dis 2011 Jan 15; 52:257
New CDC Guidelines for Treating Sexually Transmitted Diseases
Women's Health Clinical Practice Guideline Watch
Free
An additional risk-assessment question, an expanded section on adolescent STDs, and information on preferred testing procedures are among the updates.
By Diane E. Judge, APN/CNP
January 20, 2011
Covering:
Centers for Disease Control and Prevention (CDC)., MMWR Recomm Rep 2010 Dec 17; 59:1
More Support for Expanded HIV Screening and ART Access in the U.S.
Expanding HIV screening and access to antiretroviral therapy is cost-effective, whether these strategies are implemented together or individually.
By Rochelle P. Walensky, MD, MPH
January 14, 2011
Covering:
Long EF et al., Ann Intern Med 2010 Dec 21; 153:778
HIV/AIDS Year in Review 2010
Our physician-editors offer their perspective on the year's most important stories in HIV medicine.
HIV Chemoprophylaxis Proves Beneficial — and More Data Coming Soon
2010 brought proof-of-concept for antiretroviral-based vaginal microbicides and positive results from the first-ever efficacy trial of oral pre-exposure prophylaxis.
By Raphael J. Landovitz, MD, MSc
January 3, 2011
Next Steps for Tenofovir Gel After the CAPRISA 004 Trial
A host of trials are under way to help ensure rapid licensure and implementation of tenofovir gel for HIV prevention.
HIV Treatment as Prevention
Studies from 2010 highlighted the role of antiretroviral therapy in reducing HIV transmission rates, but much remains to be learned.
HIV Still Rampant Among MSM
Effective prevention programs are urgently needed.
A Giant Step Toward HIV Prevention
Drugs that treat the infection can also prevent it.
HIV/AIDS Most Read Stories of 2010
HIV/AIDS Clinical Care Letter to Readers
Free
The readers' top 10 stories from the past year
A New Rapid Test for Detection of HIV
The INSTI HIV-1 antibody test delivers results in as little as 60 seconds.
By Rochelle P. Walensky, MD, MPH
December 13, 2010
Effects of a National Human Papillomavirus Vaccination Program in Australia
Women's Health Summary and Comment
Free
Rates of genital warts dropped in both young women and heterosexual men following widespread vaccination of girls and women aged 12 to 26.
By Anna Wald, MD, MPH
December 9, 2010
Covering:
Donovan B et al., Lancet Infect Dis 2010 Nov 9
Oral Tenofovir/FTC for Pre-Exposure Prophylaxis: The iPrEx Study
HIV/AIDS Clinical Care Summary and Comment
Free
In the first-ever efficacy trial of antiretroviral-based pre-exposure prophylaxis, once-daily oral tenofovir significantly reduced the risk for HIV acquisition among men who have sex with men.
By Raphael J. Landovitz, MD
November 23, 2010
Covering:
Grant RM et al., N Engl J Med 2010 Nov 23
Michael NL., N Engl J Med 2010 Nov 23
When the Rubber Hits the Road: Paying for Expanded HIV Testing and Care
HIV/AIDS Clinical Care Summary and Comment
Free
Doubling the rate of HIV testing among U.S. adults over the next 5 years would lead to an additional 46,000 new diagnoses but would cost an additional $2.7 billion.
By Keith Henry, MD
November 22, 2010
Covering:
Martin EG et al., Value Health 2010 Oct 15
Don't Forget HIV-2
In New York City, HIV-2 infection occurs mainly among patients who were born in Africa; however, in many cases, the diagnosis is initially missed.
By Omobolaji Campbell-Yesufu, MD, and Rajesh T. Gandhi, MD
November 22, 2010
Covering:
Torian LV et al., Clin Infect Dis 2010 Dec 1; 51:1334
Unsafe in Switzerland
HIV/AIDS Clinical Care Summary and Comment
Free
Inconsistent condom use in HIV-serodiscordant couples was influenced by the use of suppressive antiretroviral therapy and by national recommendations that allow for unprotected sex under certain circumstances.
By Helmut Albrecht, MD
November 15, 2010
Covering:
Hasse B et al., Clin Infect Dis 2010 Dec 1; 51:1314
Cohen MS., Clin Infect Dis 2010 Dec 1; 51:1323
Age at Cancer Diagnosis Among People with AIDS
General Medicine Summary and Comment
HIV infection does not appear to accelerate carcinogenesis.
