HIV Exceptionalism and the Department of Unintended Consequences
Paul Sax, MD, explores the intersection of state privacy laws and quality improvement initiatives in his blog <$EMPH_O>HIV and ID Observations<$EMPH_C>.
Antiretroviral Therapy Reduces the Risk for Sexual HIV Transmission by 96%
A randomized trial confirms that treatment IS prevention.
HPTN 052 Results — Another Win for Early HIV Therapy
Paul Sax, MD, offers additional perspective on the trial results in his blog <$EMPH_O>HIV and ID Observations<$EMPH_C>.
β-HPV Does Not Increase Risk for Cutaneous Squamous Cell Carcinoma
Dermatology Summary and Comment
Investigators found no role for low-risk human papillomavirus strains in cutaneous SCC.
HPV Vaccination of Men May Prevent Cervical Cancer in Women
Dermatology Summary and Comment
Men with many sexual partners had the highest incidence of oncogenic human papillomavirus infections.
By Mark V. Dahl, MD
May 13, 2011
Covering:
Giuliano AR et al., Lancet 2011 Mar 12; 377:932
Test and Treat Among MSM in San Francisco
A model of the HIV epidemic among men who have sex with men in San Francisco demonstrates the downstream population benefits to improved HIV screening and treatment coverage.
By Rochelle P. Walensky, MD, MPH
May 2, 2011
Covering:
Charlebois ED et al., Clin Infect Dis 2011 Apr 15; 52:1046
Screening for Anal Cancer in HIV-Infected MSM
High-resolution anoscopy without any prior testing was the most cost-effective of 18 strategies assessed for initial anal cancer screening.
By Timothy Wilkin, MD, MPH
May 2, 2011
Covering:
Lam JMC et al., AIDS 2011 Mar 13; 25:635
To Pee or Not to Pee?
Women's Health Summary and Comment
Urine and endocervical samples were equally good for detecting chlamydial infections during pregnancy.
By Anna Wald, MD, MPH
April 28, 2011
Covering:
Roberts SW et al., Obstet Gynecol 2011 Apr; 117:883
Viral Shedding with Asymptomatic HSV-2 Infection
Infectious Diseases Summary and Comment
Both symptomatic and asymptomatic HSV-2 disease are associated with frequent viral shedding.
New Treatment for Chronic Hepatitis C Infection?
General Medicine Summary and Comment
Boceprevir, added to conventional therapy, raised response rates in patients with genotype 1.
By Allan S. Brett, MD
April 26, 2011
Covering:
Poordad F et al., N Engl J Med 2011 Mar 31; 364:1195
Bacon BR et al., N Engl J Med 2011 Mar 31; 364:1207
Jensen DM., N Engl J Med 2011 Mar 31; 364:1272
HIV PrEP Trial in Women Halted
Preliminary data from the FEM-PrEP trial show equal numbers of HIV infection in women taking Truvada as oral pre-exposure prophylaxis and those taking placebo.
Standard vs. Alternative Dosing Regimens for HPV Vaccine: Does It Matter?
Alternate dosing schedules within a 1-year window proved immunogenic.
The AIDS Conspiracy Theory Endures
Blacks and Hispanics were more likely to subscribe than whites, but attitudes toward research were unaffected.
By Abigail Zuger, MD
April 11, 2011
Covering:
Russell SL et al., HIV Clin Trials 2011 Jan/Feb; 12:37
Update on Pre-Exposure Prophylaxis
With the efficacy of PrEP now proven, attention at CROI 2011 turned to adherence and safety.
Pinning Down HPV's Natural History in Men
Women's Health Summary and Comment
International study reveals human papillomavirus incidence and rates of clearance.
By Anna Wald, MD, MPH
March 31, 2011
Covering:
Giuliano AR et al., Lancet 2011 Mar 12; 377:932
Monsonego J., Lancet 2011 Mar 12; 377:881
HIV Transmission from a Living Organ Donor
Infectious Diseases Summary and Comment
HIV was transmitted by transplantation of a kidney from a living donor who became infected after being tested.
By Stephen G. Baum, MD
March 30, 2011
Covering:
Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2011 Mar 18; 60:297
High-Grade AIN Among HIV-Infected Men Who Have Sex with Men
In a 3-year prospective study, the cumulative incidence of high-grade anal intraepithelial neoplasia was 37% among HIV-infected MSM receiving ART.
Putting PrEP into Practice — The Experts Respond
HIV/AIDS Clinical Care Antiretroviral Rounds
Free
Two experts describe how they would manage our latest Antiretroviral Rounds case.
Opt-Out HIV Testing: What Are We Waiting For?
Although the CDC recommends that HIV testing be performed in all clinical settings unless the patient refuses, several states still require written consent. This study shows why it's time for those laws to change.
By Carlos del Rio, MD
March 14, 2011
Covering:
April MD et al., J Gen Intern Med 2011 Feb 1
Human Papillomavirus Infections in Men: Incidence and Clearance
Infectious Diseases Summary and Comment
Among HIV-negative men in three countries, the incidence of new genital HPV infection was 38.4 cases per 1000 person-months.
By Mary E. Wilson, MD
March 9, 2011
Covering:
Giuliano AR et al., Lancet 2011 Mar 12; 377:932
Monsonego J., Lancet 2011 Mar 12; 377:881
Testing for Syphilis
Infectious Diseases Summary and Comment
Free
Reversing the sequence of screening tests has improved case identification but — in low-prevalence populations — has increased the likelihood of false-positive results.
By Richard T. Ellison III, MD
March 2, 2011
Covering:
Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2011 Feb 11; 60:133
Mishra S et al., Sex Transm Dis 2011 Mar; 38:190
Putting PrEP into Practice
HIV/AIDS Clinical Care Antiretroviral Rounds
Free
A young man who repeatedly engages in high-risk sexual activity with other men requests pre-exposure prophylaxis to prevent HIV infection. Do you oblige?
Can Behavioral Interventions Improve HIV Treatment Adherence and Viral Control?
An intensive behavioral intervention improved treatment adherence and reduced the frequency of risky sex but had no effect on virologic suppression.
Sexual Behavior in Adolescents and Young Adults: Ask, but They Might Not Tell
Ten percent of young adults with a confirmed sexually transmitted infection reported abstaining from sexual activity during the previous 12 months.
CDC Estimates Half of New HIV Infections Occur Among Black Americans
HIV/AIDS Clinical Care Summary and Comment
Free
High-risk sexual behavior continues to be the primary driver.
By Abigail Zuger, MD
February 18, 2011
Covering:
Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2011 Feb 4; 60:93
Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2011 Feb 4; 60:99
