Outcomes of TB Treatment in HIV-Infected Patients
Infectious Diseases Summary and Comment
Relapse rates were significantly higher in TB patients with HIV infection than in those without such infection.
By Neil M. Ampel, MD
June 20, 2007
Covering:
Nahid P et al., Am J Respir Crit Care Med 2007 Jun 1; 175:1199-206
Fluoroquinolones No Longer Recommended for Empirical Gonorrhea Treatment
Infectious Diseases Summary and Comment
Because of increasing gonococcal resistance to fluoroquinolones, these drugs should not be used for initial treatment of gonorrhea.
By Stephen G. Baum, MD
June 6, 2007
Covering:
Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2007 Apr 13; 56:332-6
Sexual Transmission of Hepatitis C Virus
Infectious Diseases Summary and Comment
An outbreak of hepatitis C infection among HIV-infected men who have sex with men suggests sexual transmission of the virus.
By Rajesh T. Gandhi, MD
June 6, 2007
Covering:
Danta M et al., AIDS 2007 May 11; 21:983-91
Survival Benefits of Retention in HIV Care
HIV/AIDS Clinical Care Summary and Comment
Free
Quarterly outpatient visits for HIV care improve the chances of long-term survival.
By Rochelle P. Walensky, MD, MPH
June 4, 2007
Covering:
Giordano TP et al., Clin Infect Dis 2007 Jun 1; 44:1493-9
Cheever LW., Clin Infect Dis 2007 Jun 1; 44:1500-2
New Estimates of Post-ART Survival
Clinicians and patients will soon be able to calculate 5-year survival rates online.
By Paul E. Sax, MD
June 4, 2007
Covering:
The Antiretroviral Therapy (ART) Cohort Collaboration., AIDS 2007 May 31; 21:1185-97
Can ART Reduce Sexual Transmission of HIV Among MSM?
The potential reduction in secondary HIV transmission may be offset by the longer duration of infectiousness.
By Carlos del Rio, MD
June 4, 2007
Covering:
McCormick AW et al., Clin Infect Dis 2007 Apr 15; 44:1115-22
HIV and STD Screening in the ED
Emergency Medicine Summary and Comment
A combined ED-based screening program is feasible.
By Richard D. Zane, MD, FAAEM
June 1, 2007
Covering:
Silva A et al., Ann Emerg Med 2007 May; 49:564-72
HPV Vaccine Prevents Precancerous Vulvovaginal Lesions
General Medicine Summary and Comment
No women who completed the full vaccine protocol developed lesions related to an HPV type to which they were previously susceptible.
By Bruce Soloway, MD
May 31, 2007
Covering:
Joura EA et al., Lancet 2007 May 19; 369:1693-702
Could Early and Continuous HIV Therapy Achieve Eradication?
Infectious Diseases Summary and Comment
Free
The decay rate of the HIV reservoir in patients treated early in infection raises the question of whether eradication is possible with prolonged continuous therapy.
By Daniel J. Diekema, MD, MS
May 23, 2007
Covering:
Chun TW et al., J Infect Dis 2007 Jun 15; 195:1762-4
Margolis DM and Archin NM., J Infect Dis 2007 Jun 15; 195:1734-6
HPV Vaccination Update: An Important Hurdle
Women's Health Summary and Comment
Free
The HPV vaccine was highly effective against anogenital and cervical lesions in women with no previous vaccine-specific HPV exposure.
By Sandra Ann Carson, MD
May 17, 2007
Covering:
Garland SM et al., N Engl J Med 2007 May 10; 356:1928-43
The FUTURE II Study Group., N Engl J Med 2007 May 10; 356:1915-27
Sawaya GF and Smith-McCune K., N Engl J Med 2007 May 10; 356:1991-3
Don’t Treat Gonococcal Infections with Fluoroquinolones
Women's Health Practice Watch
The rising prevalence of fluoroquinolone resistance has prompted revision of CDC treatment guidelines.
By Diane E. Judge, APN/CNP
May 17, 2007
Fluoroquinolones No Longer Recommended to Treat Gonorrhea
Emergency Medicine Summary and Comment
Free
Due to growing resistance of <$EMPH_O>N. gonorrhoeae<$EMPH_C> to fluoroquinolones, the CDC now recommends cephalosporins to treat gonorrhea and related infections.
By Diane M. Birnbaumer, MD, FACEP
May 11, 2007
Covering:
Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2007 Apr 13; 56:332-6
HPV Vaccination: Data at Last
General Medicine Summary and Comment
Free
The short-term results of a three-dose immunization schedule are impressive for many recipients. As for the long term: Still unclear.
By Abigail Zuger, MD
May 9, 2007
Covering:
Garland SM et al., N Engl J Med 2007 May 10; 356:1928-43
The FUTURE II Study Group., N Engl J Med 2007 May 10; 356:1915-27
Sawaya GF and Smith-McCune K., N Engl J Med 2007 May 10; 356:1991-3
Charo RA., N Engl J Med 2007 May 10; 356:1905-8
Agosti JM and Goldie SJ., N Engl J Med 2007 May 10; 356:1908-10
HPV-16 and Oropharyngeal Cancers
Dermatology Summary and Comment
Free
HPV infection and multiple sex partners were associated with an increased risk for oropharyngeal cancer.
By Lowell A. Goldsmith, MD, MPH
May 9, 2007
Covering:
D’Souza G et al., N Engl J Med 2007 May 10; 356:1944-56
The HPV Vaccine and Cervical Neoplasia: Not Just for Warts Anymore
Dermatology Summary and Comment
Free
Widespread immunization against HPV will reduce rates of both cervical cancer and genital warts.
By Craig A. Elmets, MD
May 9, 2007
Covering:
The FUTURE II Study Group., N Engl J Med 2007 May 10; 356:1915-27
More Than an Ounce of Prevention for HPV
Dermatology Summary and Comment
A safe and effective HPV vaccine means reduced risk for associated disease now and a hope for future vaccines.
By Craig A. Elmets, MD
May 9, 2007
Covering:
Garland SM et al., N Engl J Med 2007 May 10; 356:1928-43
Efficacy and Safety of the Quadrivalent HPV Vaccine
Infectious Diseases Summary and Comment
Free
Two randomized controlled trials provide an additional year of follow-up.
By Richard T. Ellison III, MD
May 9, 2007
Covering:
Garland SM et al., N Engl J Med 2007 May 10; 356:1928-43
The FUTURE II Study Group., N Engl J Med 2007 May 10; 356:1915-27
Sawaya GF and Smith-McCune K., N Engl J Med 2007 May 10; 356:1991-3
HPV-16 and Oropharyngeal Cancer
Infectious Diseases Summary and Comment
Free
HPV-16 infection was shown to be an independent risk factor for oropharyngeal squamous-cell carcinoma.
By Richard T. Ellison III, MD
May 9, 2007
Covering:
D’Souza G et al., N Engl J Med 2007 May 10; 356:1944-56
HIV Integrase-Inhibitor Advances
Infectious Diseases Summary and Comment
Raltegravir, the first drug in this new class of antiretroviral agents, shows promise in patients infected with multidrug-resistant virus.
By Rajesh T. Gandhi, MD
May 9, 2007
Covering:
Grinsztejn B et al., Lancet 2007 Apr 14; 369:1261-9
HIV Drug Resistance Among Infants
Infectious Diseases Summary and Comment
In nearly one quarter of HIV-infected infants, the virus was drug-resistant before initiation of treatment.
By Daniel J. Diekema, MD, MS
May 9, 2007
Covering:
Persaud D et al., J Infect Dis 2007 May 15; 195:1402-10
Treatment Responses: Getting Better All the Time
Regardless of patient demographics, immunologic and virologic outcomes improved from 1999 through 2004 in a diverse cohort in London.
By John J.W. Fangman, MD
May 7, 2007
Covering:
Lampe FC et al., Arch Intern Med 2007 Apr 9; 167:692-700
Treatment of Gonococcal Infections: No More Fluoroquinolones, Only Cephalosporins
The CDC no longer recommends fluoroquinolones for treatment of gonococcal infections.
By Peggy Sue Weintrub, MD
May 2, 2007
Covering:
Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2007 Apr 13; 56:332-6
Late Diagnosis of HIV: A Persistent Problem
Nearly half of all patients at a university clinic in the southern U.S. had AIDS at the time of their HIV diagnoses.
By Carlos del Rio, MD
April 30, 2007
Covering:
Mugavero MJ et al., Am J Med 2007 Apr; 120:370-3
Long-Term ART and Risk for Myocardial Infarction
Infectious Diseases Summary and Comment
Free
Risk for myocardial infarction increased in the DAD study with longer duration of PI use but not NNRTI use.
By Rajesh T. Gandhi, MD
April 25, 2007
Covering:
The DAD Study Group., N Engl J Med 2007 Apr 26; 356:1723-35
Stein JH., N Engl J Med 2007 Apr 26; 356:1773-5
Hughes MD and Williams PL., N Engl J Med 2007 Apr 26; 356:1705-7
Testing for HIV in the Emergency Department
HIV/AIDS Clinical Care Summary and Comment
Free
Having both a screening program and a provider referral program for HIV testing proved to be very effective for diagnosing new infections in a busy urban ED.
By Charles B. Hicks, MD
April 23, 2007
Covering:
Lyss SB et al., J Acquir Immune Defic Syndr 2007 Apr 1; 44:435-42
