Maybe They Do Listen . . .
The declining teenage pregnancy rate during the past decade is believed to be secondary to a delay in the onset of sexual activity. Results from . . .
By William P. Kanto, Jr., MD
January 12, 2006
Covering:
Sulak PJ et al., Am J Obstet Gynecol 2005 Dec; 193:1945-54
HSV Acquisition During Pregnancy
General Medicine
Summary and Comment
New data indicate that HSV acquisition rates are high in serodiscordant couples, but the results do not provide guidance on whether routine serologic screening is warranted.
By Robert W. Rebar, MD
January 10, 2006
Covering:
Gardella C et al., Am J Obstet Gynecol 2005 Dec; 193:1891-9
Alternative Strategies for Preventing Cervical Cancer
Women's Health
Summary and Comment
Current programs to prevent cervical cancer rely on regular cytologic evaluation of the cervix, with follow-up of abnormal Pap smear results. This sequence requires several . . .
By Anna Wald, MD, MPH
January 10, 2006
Covering:
Brewster WR et al., JAMA 2005 Nov 2; 294:2182-7
Denny L et al., JAMA 2005 Nov 2; 294:2173-81
False-Positive Results on Rapid HIV-Antibody Tests
HIV/AIDS Clinical Care
Summary and Comment
Free
Counselors at several HIV testing programs have reported a higher-than-expected rate of false-positive results with the OraQuick oral fluid test. The CDC, FDA, and test manufacturer are investigating.
By Paul E. Sax, MD
January 4, 2006
Covering:
Centers for Disease Control and Prevention., MMWR Morb Mortal Wkly Rep 2005 Dec 23; 54:1287-8
Selective Drug Discontinuation: Keep the NRTIs
In patients with detectable viremia on combination antiretroviral therapy, stopping the NRTI-component of the regimen led to prompt viral rebound.
By Paul E. Sax, MD
January 4, 2006
Covering:
Deeks SG et al., J Infect Dis 2005 Nov 1; 192:1537-44
Transmitted Resistance in the CASCADE Collaboration
Transmitted HIV-drug resistance appears to have increased over time in a large cohort from Europe and Canada, but what actually constitutes significant antiretroviral drug resistance?
By Charles B. Hicks, MD
January 4, 2006
Covering:
Masquelier B et al., J Acquir Immune Defic Syndr 2005 Dec 15; 40:505-11
Treatment Interruption in Patients with a High CD4 Nadir
Patients who initiated antiretroviral therapy at high CD4-cell counts and then interrupted treatment were more likely to resume therapy if they had a low CD4 nadir or a viral genotype predictive of syncytium-inducing HIV.
By Rajesh Gandhi, MD
January 4, 2006
Covering:
Toulson AR et al., J Infect Dis 2005 Nov 15; 192:1787-93
Entrance Left: The Endocrinologist
HIV/AIDS Clinical Care
Antiretroviral Rounds
A 53-year-old white man has a longstanding HIV infection that was complicated by shingles in 1996, a case of PCP in 1998, and several instances . . .
By Charles B. Hicks, MD, Polyxeni Koutkia-Mylonakis, MD, MA, and G. Sonia Nagy, MD
January 4, 2006
Pediatric HIV Treatment Guidelines Revised
Pediatric HIV treatment guidelines from DHHS/IDSA were recently updated to include information on tipranavir and on new formulations of FTC and lopinavir/ritonavir. The full text . . .