The Drug-Resistant Gonorrhea: How Much of a Threat?
Take our poll in the HIV and ID Observations blog.
DHHS Guidelines Add Tenofovir/FTC/Elvitegravir/Cobicistat as an Alternative Regimen for First-Line HIV Treatment
HIV/AIDS Clinical Care Clinical Practice Guideline Watch
Free
Tenofovir/FTC/elvitegravir/cobicistat is the first single-tablet antiretroviral regimen that includes an HIV integrase inhibitor rather than targeting reverse transcriptase alone.
By Charles B. Hicks, MD
October 1, 2012
Covering:
U.S. Department of Health and Human Services.,
It's Time to Dump the HIV Western Blot
Dr. Paul Sax makes the case in his blog HIV and ID Observations .
FDA Approves Quad for Initial HIV Treatment
Coformulated tenofovir/FTC/elvitegravir/cobicistat is now the third fixed-dose, once-daily antiretroviral regimen approved for treatment-naive HIV-infected patients.
More from HPTN 052
Initiation of antiretroviral therapy in HIV-infected adults at CD4 counts >350 cells/mm3 significantly reduced the incidence of clinical events and is cost-effective, according to two analyses presented at AIDS 2012.
The Cascade of HIV Care in the U.S.
Only 25% of HIV-infected people in the U.S. achieve virologic suppression, and that number is even lower for racial/ethnic minorities, according to data presented at AIDS 2012.
Interim Guidelines for Using PrEP in Heterosexuals
HIV/AIDS Clinical Care Clinical Practice Guideline Watch
Recommendations are similar to those for men who have sex with men but include frequent pregnancy tests for women.
By Abigail Zuger, MD
August 30, 2012
Covering:
Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2012 Aug 10; 61:586
"Quad" Approved by FDA
Dr. Paul Sax offers his insights on the new 4-in-1 pill for HIV treatment in his blog HIV and ID Observations .
Early Syphilis May Greatly Increase HIV Viral Load
Syphilis infection was associated with a transient dip in CD4-cell count and a significant increase in HIV viral load, regardless of HIV treatment status.
By Brian R. Wood, MD
August 20, 2012
Covering:
Jarzebowski W et al., Arch Intern Med 2012 Jul 23
Cervical Cancer Screening in HIV-Positive Women
Women's Health Summary and Comment
Risk for cervical dysplasia in HPV-negative women is low, regardless of HIV status.
By Anna Wald, MD, MPH
August 16, 2012
Covering:
Keller MJ et al., JAMA 2012 Jul 25; 308:362
ART Adherence Lower Among Blacks Than Whites
HIV/AIDS Clinical Care Summary and Comment
Free
The association persisted even after adjustment for demographics, depression, and substance use.
By Keith Henry, MD
August 13, 2012
Covering:
Simoni JM et al., J Acquir Immune Defic Syndr 2012 Aug 15; 60:466
Using HIV Genotypes to Identify HIV Transmission Networks
About a quarter of HIV <$EMPH_O>pol<$EMPH_C> sequences were clustered in this study of 3700 HIV-infected patients from across the U.S.
Waking Up HIV
HIV/AIDS Clinical Care Summary and Comment
Free
Vorinostat triggers HIV expression in latently infected cells from patients on antiretroviral therapy, which may be a necessary first step toward eradicating the infection.
By Rajesh T. Gandhi, MD
August 6, 2012
Covering:
Archin NM et al., Nature 2012 Jul 26; 487:482
Deeks SG., Nature 2012 Jul 26; 487:439
The HIV Epidemic in U.S. Immigrants
Infected individuals born outside the U.S. were more likely to be female and to report heterosexual acquisition than those born in the U.S.
By Abigail Zuger, MD
August 6, 2012
Covering:
Prosser AT et al., JAMA 2012 Jul 22
Katz MH., JAMA 2012 Jul 22
Really Rapid Review — 2012 International AIDS Conference, Washington, D.C.
Dr. Paul Sax offers a quick but comprehensive take on the meeting in his blog HIV and ID Observations .
HIV Screening and Testing: Are We Following Recommendations?
Women's Health Summary and Comment
A minority of OB/GYNs report recommending HIV testing for all their nonpregnant patients, despite American College of Obstetricians and Gynecologists guidelines that support the practice.
Sexually Transmitted Diseases: Office-Based Screening and Diagnostic Tests
Recent advances have broadened and strengthened the available STD tests.
By Julia C. Dombrowski, MD, MPH
July 26, 2012
STDs: Practice Prevention and Get Tested
Women's Health Patient Information
When and where to seek testing and what to expect.
Hormonal Contraception and HIV: CDC Affirms Recommendations
Women's Health Summary and Comment
Women with or at high risk for HIV infection can continue to use all hormonal contraceptive methods without restriction.
By Anna Wald, MD, MPH
July 26, 2012
Covering:
Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2012 Jun 22; 61:449
New IAS–USA Guidelines Confirm Commitment to Universal HIV Treatment
HIV/AIDS Clinical Care Clinical Practice Guideline Watch
Free
Benefits are assumed to outweigh risks at all stages of HIV infection.
By Abigail Zuger, MD
July 23, 2012
Covering:
Thompson MA et al., JAMA 2012 Jul 25; 308:387
Tenofovir/FTC Approved for PrEP . . .
. . . but issues remain regarding implementation.
Is Subclinical Pelvic Inflammatory Disease a Significant Cause of Infertility?
Women's Health Summary and Comment
Study data indicate that the answer is yes.
By Robert W. Rebar, MD
July 12, 2012
Covering:
Wiesenfeld HC et al., Obstet Gynecol 2012 Jul; 120:37
PrEP in Heterosexual Adults: Mixed Results
HIV/AIDS Clinical Care Summary and Comment
Free
A trio of studies on pre-exposure prophylaxis demonstrates proof-of-principle in heterosexual populations but highlights the need for more data from women.
By Raphael J. Landovitz, MD, MSc
July 11, 2012
Covering:
Baeten JM et al., N Engl J Med 2012 Jul 11
Thigpen MC et al., N Engl J Med 2012 Jul 11
Van Damme L et al., N Engl J Med 2012 Jul 11
Home HIV Test Big News — But Why? And What Impact Will It Have?
Dr. Paul Sax offers some perspective in his blog HIV and ID Observations .
HIV Testing in the U.S.: Good News and Bad
HIV/AIDS Clinical Care Summary and Comment
Free
Some infections are diagnosed promptly, but most are not.
By Abigail Zuger, MD
July 2, 2012
Covering:
Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2012 Jun 22; 61:441
