Extra Drugs Unnecessary in Initial HIV Treatment
General Medicine Summary and Comment
In a large study, three- and four-drug regimens were equally successful.
By Abigail Zuger, MD
September 12, 2006
Covering:
Gulick RM et al., JAMA 2006 Aug 16; 296:769-81
Colorectal Cancer Screening for HIV-Infected Patients
Infectious Diseases Summary and Comment
Don’t neglect long-term health maintenance in HIV-infected patients.
By Daniel J. Diekema, MD, MS
September 6, 2006
Covering:
Bini EJ et al., Arch Intern Med 2006 Aug 14/28; 166:1626-31
Treatment of Sexually Transmitted Diseases
Infectious Diseases Clinical Practice Guideline Watch
An update of the CDC’s 2002 guidelines
By Richard T. Ellison III, MD
September 6, 2006
Covering:
Centers for Disease Control and Prevention (CDC)., MMWR Recomm Rep 2006 Aug 4; 55:1-94
Condoms Still Important in Preventing Human Papillomavirus Infection
Dermatology Summary and Comment
Even inconsistent condom use provided considerable preventive benefit.
By Jan V. Hirschmann, MD
July 14, 2006
Covering:
Winer RL et al., N Engl J Med 2006 Jun 22; 354:2645-54
Is EBV-Associated Infectious Mononucleosis an STD?
General Medicine Summary and Comment
Does this PG-rated disease deserve an X rating?
By Abigail Zuger, MD
August 31, 2006
Covering:
Crawford DH et al., Clin Infect Dis 2006 Aug 1; 43:276-82
Atazanavir-Ritonavir Alone?
Infectious Diseases Summary and Comment
Although most patients who switched to this regimen maintained virologic suppression for at least 24 weeks, the long-term effectiveness of simplified therapy is not known.
By Rajesh T. Gandhi, MD
August 30, 2006
Covering:
Swindells S et al., JAMA 2006 Aug 16; 296:806-14
Structured Treatment Interruptions: The Jury Is Still Out
Infectious Diseases Summary and Comment
In this controlled trial, structured HIV treatment interruptions improved host control of viral replication.
By Daniel J. Diekema, MD, MS
August 30, 2006
Covering:
Jacobson JM et al., J Infect Dis 2006 Sep 1; 194:623-32
El-Sadr W et al.,
Updated Guidelines for Treatment of STDs
HIV/AIDS Clinical Care Clinical Practice Guideline Watch
Free
Changes reflect increasing antibiotic resistance for some infections and new treatment options for others.
By Abigail Zuger, MD
August 28, 2006
Covering:
MMWR Recomm Rep 2006 Aug 4; 55:1-94
Unknowing Exposure to HIV Among Young MSM
In a CDC study, young urban MSM who equated old, negative HIV test results with current serostatus potentially exposed a substantial number of new sex partners to HIV.
By Demetre C. Daskalakis, MD
August 28, 2006
Covering:
MacKellar DA et al., AIDS 2006 Aug 1; 20:1637-44
HPV Genotypes in Women with HIV
High-risk HPV types other than HPV-16 and -18 were common in HIV-infected women and were associated with cervical cytological abnormalities.
By Nicole G. Campos, MS, and Sue J. Goldie, MD, MPH
August 28, 2006
Covering:
Luque AE et al., J Infect Dis 2006 Aug 15; 194:428-34
The CDC Releases Its HPV Vaccine Recommendations
Women's Health Practice Watch
Free
The new vaccine is recommended for use in women up to age 26 and for routine administration to 11- and 12-year-old girls going forward.
By Anna Wald, MD, MPH
August 24, 2006
Four Drugs Not Better Than Three for HIV
Infectious Diseases Summary and Comment
In HIV-infected patients starting antiretroviral therapy, addition of abacavir to zidovudine, lamivudine, and efavirenz does not improve treatment results.
By Rajesh T. Gandhi, MD
August 23, 2006
Covering:
Gulick RM et al., JAMA 2006 Aug 16; 296:769-81
Do More People Get Their HIV Test Results If an Alternative Test Is Used?
Receipt of results was most common with rapid tests, according to a meta-analysis.
By Carlos del Rio, MD
August 21, 2006
Covering:
Hutchinson AB et al., AIDS 2006 Aug 1; 20:1597-604
Using Male Circumcision to Slow the Spread of HIV
Mathematical models indicate that male circumcision could substantially reduce HIV transmission in sub-Saharan Africa, with benefits greatest in areas where circumcision rates are low and HIV infection rates are high.
By G. Sonia Nagy, MD
August 21, 2006
Covering:
Williams BG et al., PLoS Med 2006 Jul; 3:e262
Therapy Outcomes Among Triply Infected Patients (HIV + HCV + GBV-C)
GB virus C infection is very common among patients coinfected with HCV and HIV; its clearance with interferon therapy is not associated with changes in HIV viral load or in CD4-cell count.
By Carlos del Rio, MD
August 21, 2006
Covering:
Schwarze-Zander C et al., J Infect Dis 2006 Aug 15; 194:410-9
Berzsenyi MD and Roberts SK., J Infect Dis 2006 Aug 15; 194:407-9
Cancer and AIDS: A Mixed Report Card
Infectious Diseases Summary and Comment
Despite sizeable declines in Kaposi sarcoma and non-Hodgkin lymphoma, these and other cancers continue to occur at high rates in individuals with AIDS.
By Rajesh T. Gandhi, MD
August 16, 2006
Covering:
Engels EA et al., AIDS 2006 Aug 1; 20:1645-54
Has Progress in Early Virologic Response with Antiretrovirals Translated into Better Clinical Outcomes?
HIV/AIDS Clinical Care Summary and Comment
Free
Not according to a large international study tracking antiretroviral research from 1995 to 2003
By Abigail Zuger, MD
August 14, 2006
Covering:
The Antiretroviral Therapy (ART) Cohort Collaboration., Lancet 2006 Aug 5; 368:451-8
Prevalence of HPV Infection in the U.S.
Infectious Diseases Summary and Comment
The high prevalence of human papillomavirus infection among sexually active women supports a strategy of early, widespread vaccination.
By Daniel J. Diekema, MD, MS
August 9, 2006
Covering:
Manhart LE et al., Sex Transm Dis 2006 Aug; 33:502-8
New Data on HIV Risk Behavior Among Affluent Urban MSM
A full 30% of the MSM surveyed were not adhering to the recommendation for yearly HIV testing.
By Abigail Zuger, MD
July 31, 2006
Covering:
Centers for Disease Control and Prevention., MMWR Morb Mortal Wkly Rep 2006 Jul 7; 55:1-16
One Pill, Once Daily: Now an Option for HIV Patients
The new (and long-awaited) tenofovir/FTC/efavirenz coformulation should be an effective option for treatment-naive patients, as well as for some treatment-experienced patients who want to reduce their pill burden.
By Paul E. Sax, MD
July 31, 2006
Can Consistent Condom Use Contain HPV?
Women's Health Summary and Comment
Among newly sexually active young women, consistent condom use reduces the transmission of HPV.
By Andrew M. Kaunitz, MD
July 20, 2006
Covering:
Winer RL et al., N Engl J Med 2006 Jun 22; 354:2645-54
Steiner MJ and Cates W Jr., N Engl J Med 2006 Jun 22; 354:2642-3
Dyslipidemia Improves After Replacing Stavudine with Tenofovir
Infectious Diseases Summary and Comment
HIV-infected patients who changed from stavudine to tenofovir showed improvements in dyslipidemia and cardiovascular risk.
By Rajesh T. Gandhi, MD
July 19, 2006
Covering:
Llibre JM et al., AIDS 2006 Jun 26; 20:1407-14
HIV/AIDS Among Women in the Southern U.S.
The HIV epidemic among southern women is characterized by heterosexual acquisition, a disproportionate effect on blacks, a high proportion of cases in rural areas, and multiple high-risk behaviors.
By Rebeca Plank, MD
July 17, 2006
Covering:
Fleming PL et al., Sex Transm Dis 2006 Jul; 33:S32-8
Condoms Prevent the Transmission of Human Papillomavirus
This prospective study clearly shows that condoms protect against HPV.
By Peggy Sue Weintrub, MD
July 12, 2006
Covering:
Winer RL et al., N Engl J Med 2006 Jun 22; 354:2645-54
Steiner MJ and Cates W Jr., N Engl J Med 2006 Jun 22; 354:2642-3
Condom Use Reduces Risk for HPV Infection in Women
Infectious Diseases Summary and Comment
The incidence of genital human papillomavirus infections was greatly reduced in young women whose male sexual partners consistently used condoms.
By Neil R. Blacklow, MD
July 12, 2006
Covering:
Winer RL et al., N Engl J Med 2006 Jun 22; 354:2645-54
