How Much Sunlight Is Equivalent to Vitamin D Supplementation?
Dermatology Summary and Comment
Free
Now is the winter of our vitamin D discontent.
By Craig A. Elmets, MD
June 4, 2010
Covering:
Terushkin V et al., J Am Acad Dermatol 2010 Jun; 62:929
Tsiaras WG and Weinstock MA., J Am Acad Dermatol 2010 Jun; 62:935
Photodynamic Therapy for Preventing Skin Cancers in Transplant Recipients?
Dermatology Summary and Comment
This therapy may help prevent squamous cell carcinomas.
Adipophilin Antibody: A New Marker for Sebaceous Differentiation
Dermatology Summary and Comment
Staining for adipophilin antibody identified 100% of sebaceous carcinomas.
By Angelica Selim, MD
May 21, 2010
Covering:
Ostler DA et al., Mod Pathol 2010 Apr; 23:567
A Common Pathway for Ultraviolet Radiation–Induced Immunosuppression
Dermatology Summary and Comment
Free
UV light induces immunosuppression, and the process appears to be linked to mechanisms of DNA repair.
By Craig A. Elmets, MD
May 14, 2010
Covering:
Sreevidya CS et al., J Invest Dermatol 2010 May; 130:1428
Halliday GM., J Invest Dermatol 2010 May; 130:1209
Kaposi Meets Vincristine
Dermatology Summary and Comment
Intralesional vincristine was associated with a high rate of remission of lesions.
By Mark V. Dahl, MD
May 14, 2010
Covering:
Brambilla L et al., Br J Dermatol 2010 Apr; 162:854
The Photoaging Gene
Dermatology Summary and Comment
Severe photoaging is connected to age, but also to certain variants in <$EMPH_O>MC1R<$EMPH_C>.
By Mark V. Dahl, MD
May 7, 2010
Covering:
Elfakir A et al., J Invest Dermatol 2010 Apr; 130:1107
Gene Forecasters: Prognostic Markers for CTCL
Dermatology Summary and Comment
Genetic analysis can indicate risk for progression and outcomes in patients with cutaneous T-cell lymphoma.
By Craig A. Elmets, MD
May 7, 2010
Covering:
Litvinov IV et al., Clin Cancer Res 2010 Apr 1; 16:2106
Lip and Tip SNPs
Dermatology Summary and Comment
A genetic variant may indicate mutually exclusive susceptibility to vitiligo or melanoma.
Differentiated VIN to Squamous Cell Carcinoma: p53 Role
Dermatology Summary and Comment
The p53 protein appears to have a role in the evolution of vulvar squamous cell carcinoma.
By Angelica Selim, MD
April 23, 2010
Covering:
Pinto AP et al., Mod Pathol 2010 Mar; 23:404
Cutting It Close
Dermatology Summary and Comment
Free
Partial punch biopsies are risky in pigmented lesions.
Parkinson Disease and Increased Melanoma Risk
Dermatology Summary and Comment
Evidence suggests that annual skin examination is reasonable for patients with Parkinson disease.
Coal Tar for Skin Disease: Is It Safe?
Dermatology Summary and Comment
After years of use, patients using topical coal tar for psoriasis or eczema had no excess risk for skin cancer or other malignancy.
By Craig A. Elmets, MD
April 9, 2010
Covering:
Roelofzen JHJ et al., J Invest Dermatol 2010 Apr; 130:953
Medallion-Like Dermal Dendrocyte Hamartoma: Another CD34+ Spindle-Cell Tumor
Dermatology Summary and Comment
How to differentiate DH from dermatofibrosarcoma protuberans
By Angelica Selim, MD
March 26, 2010
Covering:
Kutzner H et al., Am J Surg Pathol 2010 Feb; 34:190
Cutaneous Clear Cell Sarcoma: Insights from a Rare Entity
Dermatology Summary and Comment
The immunoprofiles of CCS and malignant melanoma overlap, so looking for genetic markers is important.
By Angelica Selim, MD
March 26, 2010
Covering:
Hantschke M et al., Am J Surg Pathol 2010 Feb; 34:216
Melanoma — Plus Ça Change . . .
Dermatology Summary and Comment
Review of melanomas by a multidisciplinary tumor board resulted in revisions of diagnoses in many patients.
By Hensin Tsao, MD, PhD
March 19, 2010
Covering:
Santillan AA et al., J Clin Oncol 2010 Jan 20; 28:481
Blastic Plasmacytoid Dendritic Cell Neoplasm: Clinical and Phenotypic Variability
Dermatology Summary and Comment
The clinical manifestations are various, and the phenotype is also multifaceted.
By Angelica Selim, MD
March 5, 2010
Covering:
Cota C et al., Am J Surg Pathol 2010 Jan; 34:75
Preventing Wrong-Site Surgery
Dermatology Summary and Comment
Free
Identifying a well-healed biopsy site can be difficult; preoperative photography can help.
By George J. Hruza, MD
February 19, 2010
Covering:
McGinness JL and Goldstein G., Dermatol Surg 2010 Feb; 36:194
Ke M et al., Dermatol Surg 2010 Feb; 36:198
Voriconazole, Chronic Photosensitivity, and Melanoma
Dermatology Summary and Comment
Five melanomas developed in two patients on voriconazole therapy.
Skin Diseases in Organ Transplant Recipients
Dermatology Summary and Comment
As transplant recipients live longer, they experience more complications of long-term immunosuppression.
By Craig A. Elmets, MD
February 19, 2010
Covering:
Wisgerhof HC et al., Br J Dermatol 2010 Feb; 162:390
Heart of Darkness
Dermatology Summary and Comment
Researchers sequence a single melanoma completely and find evidence of exposure to solar radiation within.
By Hensin Tsao, MD, PhD
February 12, 2010
Covering:
Pleasance ED et al., Nature 2010 Jan 14; 463:191
Malignancy Is (Still) Associated with Dermatomyositis
Dermatology Summary and Comment
Skin changes signal cancer risk in patients with idiopathic inflammatory myopathy.
Ca and D
Dermatology Summary and Comment
Higher serum 25(OH)D levels were associated with lower levels of nonmelanoma skin cancer in elderly men.
By Mark V. Dahl, MD
January 29, 2010
Covering:
Tang JY et al., Cancer Causes Control 2009 Nov 18
Chronic Voriconazole Use and SCCs
Dermatology Summary and Comment
Rapid development of squamous cell carcinomas is a risk in chronic voriconazole use.
Squamous Cell Carcinoma Complicates Hidradenitis Suppurativa
Dermatology Summary and Comment
Hidradenitis suppurativa (HS) is a chronic inflammatory disorder of unknown etiology that affects the intertriginous surfaces, including the axilla, inframammary region, inguinal skin, and buttocks. . . .
An Aspirin a Day Keeps the Surgeon Away
Dermatology Summary and Comment
Does celecoxib's preventive effect outweigh the possible risks?
