No Need to Fry Basal Cell Carcinomas
Dermatology
Summary and Comment
Free
Uncomplicated primary BCCs are candidates for curettage alone.
By George J. Hruza, MD
July 14, 2006
Covering:
Barlow JO et al., J Am Acad Dermatol 2006 Jun; 54:1039-45
Genetic Supervision of Melanoma by MC1R
Dermatology
Summary and Comment
Chronic sun damage and mutations in two genes interact in the development of melanoma.
By Hensin Tsao, MD, PhD
September 1, 2006
Covering:
Landi MT et al., Science 2006 Jul 28; 313:521-2
Skin Resurfacing for Skin Cancer Prevention
Dermatology
Summary and Comment
Free
Three resurfacing modalities were equally effective, so the difference may come down to cost.
By George J. Hruza, MD
August 25, 2006
Covering:
Hantash BM et al., Arch Dermatol 2006 Aug; 142:976-82
Melanoma Signatures Come of Age
Dermatology
Summary and Comment
Free
Gene expression profiling identified predictors of outcome in melanoma.
By Hensin Tsao, MD, PhD
July 28, 2006
Covering:
Winnepenninckx V et al., J Natl Cancer Inst 2006 Apr 5; 98:472-82
Two Melanoma-Related Mutations Tend to Occur Together
General Medicine
Summary and Comment
These findings demonstrate an association between <$EMPH_O>MC1R<$EMPH_C> and <$EMPH_O>BRAF,<$EMPH_C> each of which increases risk for melanoma.
By Anthony L. Komaroff, MD
July 20, 2006
Covering:
Landi MT et al., Science 2006 Jun 29
Meta-Analysis of AKs and Imiquimod
Dermatology
Summary and Comment
Free
When it comes to topical treatment for actinic keratoses, imiquimod offers some pluses.
By George J. Hruza, MD
June 27, 2006
Covering:
Hadley G et al., J Invest Dermatol 2006 Jun; 126:1251-5
Update on Risk for Infection and Malignancy with Anti-TNF Antibody Therapy
Dermatology
Summary and Comment
Not surprisingly, a meta-analysis of TNF inhibitor trials showed increased adverse events, but do findings hold up for dermatology patients?
By Jeffrey P. Callen, MD
June 27, 2006
Covering:
Bongartz T et al., JAMA 2006 May 17; 295:2275-85
Kavanaugh A and Cush JJ., 2006 May 30
Mel-5 Immunostains for Mohs Surgery Melanoma Margins
Dermatology
Summary and Comment
A valuable augmentation to the use of frozen sections
By George J. Hruza, MD
June 13, 2006
Covering:
Bhardwaj SS et al., Dermatol Surg 2006 May; 32:690-7
Tanorexics Beware: The Evidence Mounts That Indoor Tanning Is Addictive
Dermatology
Summary and Comment
Ultraviolet light exposure may have druglike effects.
By Mary Wu Chang, MD
April 25, 2006
Covering:
Kaur M et al., J Am Acad Dermatol 2006 Apr; 54:709-11
The Cost of Mohs Surgery vs. Excision
Dermatology
Summary and Comment
Free
This cost-effectiveness analysis might benefit from a longer follow-up period.
By George J. Hruza, MD
March 28, 2006
Covering:
Essers BA et al., Arch Dermatol 2006 Feb; 142:187-94
Curettage and Electrodesiccation of Low-Risk SCCs Apparently Effective in Organ Transplant Recipients
Dermatology
Summary and Comment
Free
Nevertheless, more aggressive treatment may still be warranted.
By Jeffrey P. Callen, MD
February 28, 2006
Covering:
De Graaf YGL et al., Br J Dermatol 2006 Mar; 154:493-7
Prognosis in Melanoma with Associated Dermatomyositis Depends on Stage
Dermatology
Summary and Comment
Dermatomyositis (DM) is known to be associated with cancer, and prognosis is poor in patients who have both DM and a malignancy. Reports of DM . . .
By Jeffrey P. Callen, MD
February 28, 2006
Covering:
Schiller M et al., J Am Acad Dermatol 2006 Feb; 54:221-6