Premature Aging Takes the Heat with Infrared
Dermatology Summary and Comment
Free
Infrared A radiation increased levels of the collagen-degrading enzyme MMP-1 and depleted cutaneous antioxidents.
By Craig A. Elmets, MD
October 17, 2008
Covering:
Schroeder P et al., J Invest Dermatol 2008 Oct; 128:2491
End Nodes . . .
Dermatology Summary and Comment
Free
Tumor burden predicts additional involvement, perhaps preventing unnecessary complete lymph node dissections.
By Hensin Tsao, MD, PhD
October 10, 2008
Covering:
Gershenwald JE et al., J Clin Oncol 2008 Sep 10; 26:4296
Dermatology Summary and Comment
IFN-
By Angelica Selim, MD
October 10, 2008
Covering:
Wang W et al., J Invest Dermatol 2008 Aug; 128:1997
Primary Cutaneous Small/Medium CD4+ T-Cell Lymphomas: From Indolent to Deadly
Dermatology Summary and Comment
Clinicopathologic features distinguish subtypes of these tumors with different outcomes.
By Angelica Selim, MD
October 3, 2008
Covering:
Garcia-Herrera A et al., J Clin Oncol 2008 Jul 10; 26:3364
Do Moisturizers Promote the Development of Nonmelanoma Skin Cancers?
Dermatology Summary and Comment
Free
The findings have been widely reported in the press, but the evidence is not definitive, and applicability remains to be proved.
By Craig A. Elmets, MD
September 5, 2008
Covering:
Lu Y-P et al., J Invest Dermatol 2008 Aug 14
How to Predict DNA Mismatch Repair Status: Location, Location, Location
Dermatology Summary and Comment
Sebaceous neoplasms on the trunk and extremities are more likely to contain mismatch repair defects, which are associated with Muir-Torre syndrome and malignancy.
By Angelica Selim, MD
August 22, 2008
Covering:
Singh RS et al., Am J Surg Pathol 2008 Jun; 32:936
Melanonychia: A Question of Density
Dermatology Summary and Comment
Free
The most reliable histologic factor for distinguishing benign subungual pigmented lesions from melanoma was the number of melanocytes per millimeter.
By Angelica Selim, MD
August 8, 2008
Covering:
Amin B et al., Am J Surg Pathol 2008 Jun; 32:835
Shedding Light on the Rise of Melanoma in Young Women
Women's Health Summary and Comment
More time in the sun and on tanning beds could be responsible.
Vitamin D and Death
Dermatology Summary and Comment
Free
Low levels of vitamin D spell higher risk for Death.
By Mark V. Dahl, MD
August 1, 2008
Covering:
Dobnig H et al., Arch Intern Med 2008 Jun 23; 168:1340
Folliculotropic Mycosis Fungoides: A Distinct Entity
Dermatology Summary and Comment
This aggressive variant had a worse prognosis than classic MF, at least at early stages.
By Angelica Selim, MD
August 1, 2008
Covering:
Gerami P et al., Arch Dermatol 2008 Jun; 144:738
Which Squamous Cell Carcinomas Are the Bad Actors?
Dermatology Summary and Comment
Free
Tumor thickness, immunosuppression, location on the ear, and horizontal size were associated with increased risk for metastasis in cutaneous SCC.
Management of Depression in Cancer Patients
Psychiatry Summary and Comment
Nurses provided effective, and cost-effective, depression care.
Lichen Sclerosus and Borrelia burgdorferi : Are We Missing the Link?
Dermatology Summary and Comment
Focus-floating microscopy may be useful for establishing the role of <$EMPH_O>Borrelia burgdorferi<$EMPH_C> in LS.
By Angelica Selim, MD
July 11, 2008
Covering:
Eisendle K et al., Arch Dermatol 2008 May; 144:591
White KP et al., Arch Dermatol 2008 May; 144:662
A Rare Variant Dermatofibroma with Risk for Local Recurrence and Metastasis
Dermatology Summary and Comment
These deep fibrous histiocytomas can be aggressive, especially if not completely excised.
By Angelica Selim, MD
June 20, 2008
Covering:
Gleason BC and Fletcher CDM., Am J Surg Pathol 2008 Mar; 32:354
Genotypes for Pigmentation and Skin Cancer
Dermatology Summary and Comment
Free
We are constantly learning more, but translation into practice and prevention lies in the future.
By Hensin Tsao, MD, PhD
June 6, 2008
Covering:
Sulem P et al., Nat Genet 2008 May 18
Gudbjartsson DF et al., Nat Genet 2008 May 18
Brown KM et al., Nat Genet 2008 May 18
Melanoma Prognosis Based on Anatomic Site
Dermatology Summary and Comment
Free
We don’t know why, but location affects prognosis.
By George J. Hruza, MD
May 16, 2008
Covering:
Lachiewicz AM et al., Arch Dermatol 2008 Apr; 144:515
Shedding Light on Perceptions of Indoor Tanning
Dermatology Summary and Comment
Knowledge about the ill effects of this practice is rising, but so is usage among the young.
By Craig A. Elmets, MD
May 9, 2008
Covering:
Robinson JK et al., Arch Dermatol 2008 Apr; 144:484
PEComas: A Recently Described Tumor to Keep in Mind
Dermatology Summary and Comment
Increased awareness of this tumor type will help us avoid misdiagnosis and needless anxiety.
By Angelica Selim, MD
May 9, 2008
Covering:
Liegl B et al., Am J Surg Pathol 2008 Apr; 32:608
Primary Cutaneous B-Cell Lymphomas: Radiotherapy or Chemotherapy?
Dermatology Summary and Comment
Analysis by WHO-EORTC type identified which lymphomas can be effectively treated by radiotherapy alone and which need more-aggressive treatment.
By Angelica Selim, MD
April 4, 2008
Covering:
Senff NJ et al for the Dutch Cutaneous Lymphoma Group., Arch Dermatol 2007 Dec; 143:1520
Geographic Variation, UV Exposure, and Risk for Skin Cancer
General Medicine Summary and Comment
Risk for squamous cell cancer was associated strongly with living in states where the UV index is high.
Atypical Genital Nevi
Dermatology Summary and Comment
Free
Awareness of a unique subtype of pigmented vulvar lesion will prevent misdiagnosis of melanoma.
By Angelica Selim, MD
March 14, 2008
Covering:
Gleason BC et al., Am J Surg Pathol 2008 Jan; 32:51
SCC of the Vulva Associated with HPV Infection
Dermatology Summary and Comment
The incidence of HPV-associated SCC of the vulva is increasing.
By Angelica Selim, MD
March 14, 2008
Covering:
Sutton BC et al., Mod Pathol 2008 Mar; 21:345
Geographic Variation and Skin Cancer
Dermatology Summary and Comment
Residence in sunny or high-altitude locales increased risks for basal cell and squamous cell carcinomas in a large cohort.
By George J. Hruza, MD
March 14, 2008
Covering:
Qureshi AA et al., Arch Intern Med 2008 Mar 10; 168:501
"I’ve Told You a Hundred Times" Works for Sun Protection
Dermatology Summary and Comment
In Australia, after years of educational efforts, more folks have taken to covering up while playing outdoors.
By Craig A. Elmets, MD
March 14, 2008
Covering:
Dixon HG et al., Cancer Epidemiol Biomarkers Prev 2008 Feb; 17:428
Melanoma-Initiating Cells and Therapy
Dermatology Summary and Comment
Specific targeting of tumor-initiating cells may allow us to eradicate cancers resistant to systemic therapy.
