M. bovis TB Increasing Among Hispanics in the U.S.
Infectious Diseases
Summary and Comment
Subscription required
From 1994 through 2005, <$EMPH_O>Mycobacterium bovis<$EMPH_C> accounted for 45% of pediatric TB cases and 8% of all TB cases in San Diego County, California.
Inhaled Liposomal Amphotericin B for Prevention of IPA
Infectious Diseases
Summary and Comment
Subscription required
Among patients with prolonged neutropenia, liposomal amphotericin B performed significantly better than placebo in preventing invasive pulmonary aspergillosis.
By Neil M. Ampel, MD
May 14, 2008
Covering:
Rijnders BJ et al., Clin Infect Dis 2008 May 1; 46:1401
Does Supplemental Oxygen Keep Infants with Bronchiolitis in the Hospital?
Pediatrics and Adolescent Medicine
Summary and Comment
Subscription required
Oxygen supplementation determines length of stay in hospitalized infants with bronchiolitis when the oxygen threshold is <94% SpO2 .
Rapid Screening for MDR-TB
Infectious Diseases
Summary and Comment
Free
A molecular probe was 99% sensitive and specific for multidrug TB resistance, compared with standard drug-susceptibility testing; results were available in 1 to 2 days.
By Neil M. Ampel, MD
April 23, 2008
Covering:
Barnard M et al., Am J Respir Crit Care Med 2008 Apr 1; 177:787
Legionella as a Cause of CAP
Infectious Diseases
Summary and Comment
Subscription required
<$EMPH_O>Legionella<$EMPH_C> species were the causative organisms in 3.8% of patients with community-acquired pneumonia in Germany.
By Neil M. Ampel, MD
April 16, 2008
Covering:
von Baum H et al., Clin Infect Dis 2008 May 1; 46:1356
Factors Affecting CAP Outcome
Infectious Diseases
Summary and Comment
Subscription required
In a large retrospective study, using guideline-compliant treatment and establishing an etiologic diagnosis were associated with shorter LOS and lower risk for late in-hospital mortality.
By Thomas Glück, MD
April 16, 2008
Covering:
Garau J et al., Clin Microbiol Infect 2008 Mar 5; 14:322
TB by Transplant
Infectious Diseases
Summary and Comment
Subscription required
TB was transmitted from a donor with unrecognized infection to two organ recipients.
By Stephen G. Baum, MD
April 16, 2008
Covering:
Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2008 Apr 4; 57:333
Antibiotics in Acute Rhinosinusitis: Often Prescribed, but Rarely Indicated
General Medicine
Summary and Comment
Free
No clinical signs or symptoms identified a subgroup of patients who derived benefit from antibiotics.
By Bruce Soloway, MD
April 15, 2008
Covering:
Young J et al., Lancet 2008 Mar 15; 371:908
Effects of Statins and ACE Inhibitors in CAP and Influenza
Infectious Diseases
Summary and Comment
Subscription required
An analysis of VA data indicates that, at least in men, statin or ACE inhibitor use is associated with decreased mortality from community-acquired pneumonia or influenza.
By Thomas Glück, MD
April 2, 2008
Covering:
Mortensen EM et al., Eur Respir J 2008 Mar; 31:611
Fluoroquinolones: Treating TB Reduces Pneumococcal Susceptibility
Infectious Diseases
Summary and Comment
Subscription required
The use of fluoroquinolones to treat MDR-TB was associated with the emergence of pediatric invasive pneumococcal disease caused by levofloxacin-nonsusceptible organisms.
By Mary E. Wilson, MD
April 2, 2008
Covering:
von Gottberg A et al., Lancet 2008 Mar 29; 371:1108