Cervical Conization Affects Pregnancy Outcomes
Women's Health
Summary and Comment
Free
Removal of cervical tissue raised risk for future preterm delivery, severe low birth weight, and perinatal mortality.
By Wendy S. Biggs, MD
October 16, 2008
Covering:
Albrechtsen S et al., BMJ 2008 Sep 18; 337:a1343
Arbyn M et al., BMJ 2008 Sep 18; 337:a1284
Benefits of Minimizing Barriers to IUD Insertion
Women's Health
Summary and Comment
Free
IUD insertion immediately after screening tests or surgical abortions boosted device use; IUD insertion on the day of abortion also diminished likelihood of repeat abortions.
By Diane E. Judge, APN/CNP
October 9, 2008
Covering:
Goodman S et al., Contraception 2008 Aug; 78:136
Goodman S et al., Contraception 2008 Aug; 78:143
Topiramate Use During Pregnancy and Risk for Birth Defects
Neurology
Summary and Comment
This report from the U.K. Epilepsy and Pregnancy Register highlights concerns about use of topiramate during childbearing years in women being treated for a variety of disorders.
By Page B. Pennell, MD
October 7, 2008
Covering:
Hunt S et al., Neurology 2008 Jul 22; 71:272
Recurrent Colonization with Group B Strep in Pregnancy
General Medicine
Summary and Comment
Previous genitourinary colonization with GBS during pregnancy substantially raised risk for colonization in the next pregnancy.
By Robert W. Rebar, MD
September 30, 2008
Covering:
Turrentine MA and Ramirez MM., Obstet Gynecol 2008 Aug; 112:259
Chronic Hypertension Associated with Fetal Growth Restriction
General Medicine
Summary and Comment
Analysis of a large longitudinal sample of pregnancies showed that chronic hypertension raised risk for small-for-gestational-age births in both term and preterm pregnancies.
By Robert W. Rebar, MD
September 30, 2008
Covering:
Catov JM et al., Obstet Gynecol 2008 Aug; 112:290
Cocoa Butter Debunked
Women's Health
Summary and Comment
A randomized, placebo-controlled trial showed no benefit of cocoa butter lotion in preventing stretch marks.
Novel Approach to Infant Influenza
Maternal influenza immunization reduced influenza illness in infants and respiratory illness with fever in infants and mothers.
Birth Defects and Maternal Diabetes Mellitus: All Is Not Sweetness
Pregestational DM is associated with a broader range of birth defects than is gestational DM, and the association between gestational DM and birth defects is limited mostly to overweight and obese women.
Novel Approach to Infant Influenza
General Medicine
Summary and Comment
Influenza immunization during pregnancy attenuated influenza in infants and respiratory illness with fever in infants and in mothers.
Effects of Diabetes Can Go Beyond Mom
Women's Health
Summary and Comment
Free
Pregestational diabetes was associated with a wider range of birth defects than was gestational diabetes.
Does Fetal Exposure to Magnesium Sulfate Prevent Cerebral Palsy in Preterm Infants?
Women's Health
Summary and Comment
Magnesium sulfate, administered maternally before preterm birth, attenuated risk for moderate or severe CP.
Assisted Reproductive Technology and Perinatal Outcomes
Women's Health
Summary and Comment
Rates of preterm delivery, low birth weight, and perinatal death were similar for ART pregnancies and spontaneous pregnancies.
By Anna Wald, MD, MPH
September 11, 2008
Covering:
Romundstad LB et al., Lancet 2008 Aug 30; 372:737
Andersen AN et al., Lancet 2008 Aug 30; 372:694
For Unexplained Infertility, Does Intervention Help?
Women's Health
Summary and Comment
Neither clomiphene citrate nor unstimulated intrauterine insemination led to better outcomes than did expectant management.
Spontaneous Pregnancy While Awaiting Assisted Reproductive Technology
Women's Health
Summary and Comment
Approximately 9% of Dutch women who were waiting for treatment with ART became pregnant before beginning therapy.
Ovarian Transplantation
Women's Health
Summary and Comment
Eight women with premature ovarian failure received transplants from their identical twins; six have conceived, and three have given birth.
Does Magnesium Sulfate Prevent Cerebral Palsy?
General Medicine
Summary and Comment
This placebo-controlled trial provides further evidence for the neuroprotective effect of magnesium sulfate.
By Howard Bauchner, MD
September 9, 2008
Covering:
Rouse DJ et al., N Engl J Med 2008 Aug 28; 359:895
Stanley FJ and Crowther C., N Engl J Med 2008 Aug 28; 359:962
Eat Differently and Avoid Preeclampsia?
Women's Health
Summary and Comment
Women in the highest quartile of dietary fiber intake during early pregnancy had lower triglyceride levels and preeclampsia risk.
By Wendy S. Biggs, MD
August 27, 2008
Covering:
Qiu C et al., Am J Hypertens 2008 Aug; 21:903
Is Expectant Management Indicated for Unexplained Infertility?
General Medicine
Summary and Comment
Editorialists note that in vitro fertilization appears to be the most cost-effective intervention based on current evidence.
By Robert W. Rebar, MD
August 21, 2008
Covering:
Bhattacharya S et al., BMJ 2008 Aug 7; 337:a716
El-Toukhy TA and Khalaf Y., BMJ 2008 Aug 7; 337:a772
Preeclampsia and Subsequent Renal Disease
Women's Health
Summary and Comment
History of preeclampsia was associated with greater likelihood of developing ESRD.
By Sandra Ann Carson, MD
August 20, 2008
Covering:
Vikse BE et al., N Engl J Med 2008 Aug 21; 359:800
Thadhani R and Solomon CG., N Engl J Med 2008 Aug 21; 359:858
Topiramate: Another Concern About Teratogenicity
Psychiatry
Summary and Comment
The rate of major congenital malformations in children born to women who took topiramate during pregnancy was higher than the historical background rate in the U.K.
By Deborah Cowley, MD
August 18, 2008
Covering:
Hunt S et al., Neurology 2008 Jul 22; 71:272
Pregnancy Worsens Breast Cancer Outcomes
Women's Health
Summary and Comment
Six-year risk for death was greater when breast cancer was diagnosed during or within 1 year after pregnancy.
Pregnancy-Related MI Is on the Rise
Women's Health
Summary and Comment
Incidence of pregnancy-related MI has risen, but mortality rates have declined; risks and benefits must be weighed when making treatment decisions.
By JoAnne M. Foody, MD
August 14, 2008
Covering:
Roth A and Elkayam U., J Am Coll Cardiol 2008 Jul 15; 52:171
Topiramate: Another Concern About Teratogenicity
The rate of major congenital malformations in children born to women who took topiramate during pregnancy was higher than the historical background rate in the U.K.
Do Soy Foods Affect Sperm Quality?
General Medicine
Summary and Comment
The evidence is not strong enough to recommend that men should shun tofu.
Urinalysis or Urine Protein–Creatinine Ratio for Predicting Proteinuria During Pregnancy?
Women's Health
Summary and Comment
Free
Urine protein–creatinine ratio was more sensitive than dipstick urinalysis as a screening test for proteinuria.