Elective Induction of Labor at Term: Maternal and Perinatal Outcomes
Women's Health
Summary and Comment
Induction might not be associated with excess risk for cesarean delivery.
Effect of Induction on Course of Labor
Women's Health
Summary and Comment
Extended latent phase may not indicate need for cesarean delivery.
Intrapartum Maternal Fever: Cervical Exams No Longer a Culprit
Women's Health
Summary and Comment
Risk for maternal fever during term labor did not significantly increase with number of cervical exams.
Modest Reassurance Regarding Tenofovir Use During Pregnancy
In utero exposure to tenofovir was not associated with pregnancy complications or with poor infant outcomes.
By Keith Henry, MD
June 11, 2012
Covering:
Gibb DM et al., PLoS Med 2012 May 15; 9:e1001217
Balancing Positive and Negative Effects of Antidepressants During Pregnancy
Psychiatry
Summary and Comment
Free
Auditory sensory gating was impaired in infants whose mothers had prenatal anxiety but not in those whose mothers used antidepressants during pregnancy.
By Barbara Geller, MD
June 11, 2012
Covering:
Hunter SK et al., Am J Psychiatry 2012 Jun 1; 169:616
Cesarean Delivery: Not Worth It to Irrigate
Women's Health
Summary and Comment
Abdominal irrigation increased likelihood of intraoperative nausea without lowering risk for postoperative infection.
Prenatal Antibodies to Gluten Protein, but Not Casein, Linked to Psychosis
Psychiatry
Summary and Comment
Very high levels of maternal antibodies that cross the placenta are associated with elevated risk for nonaffective psychosis.
By Barbara Geller, MD
May 25, 2012
Covering:
Karlsson H et al., Am J Psychiatry 2012 Apr 25
Birth Control That Really Works
Women's Health
Summary and Comment
Free
In the Contraceptive CHOICE project, IUDs and implants were 20 times more effective than pills, patches, or rings.
Clot or Not? Imaging Challenges in Pregnant and Postpartum Women
Women's Health
Summary and Comment
A single compression ultrasound probably is sufficient to diagnose DVT, but magnetic resonance imaging for pelvic venous thrombosis seems inaccurate.
By Allison Bryant, MD, MPH
May 17, 2012
Covering:
Le Gal G et al., BMJ 2012 Apr 24; 344:e2635
Khalil H et al., Am J Obstet Gynecol 2012 Apr
James AH., Am J Obstet Gynecol 2012 Apr; 206:276
Maternal Obesity May Increase Risk for Autism
More evidence that maternal metabolic conditions during pregnancy are associated with neurodevelopmental disorders in children.
By Louis M. Bell, MD
May 16, 2012
Covering:
Krakowiak P et al., Pediatrics 2012 May; 129:e1121
Likelihood of Bipolar Outcome Is Elevated with Postpartum Onset of Psychiatric Illness
Psychiatry
Summary and Comment
Free
Women with illness presenting in the first postpartum month are particularly at risk.
By Steven Dubovsky, MD
May 14, 2012
Covering:
Munk-Olsen T et al., Arch Gen Psychiatry 2012 Apr; 69:428
Risk for Birth Defects with Assisted Reproductive Technology: Higher or Not?
Women's Health
Summary and Comment
Free
Excess risk is small and may be related primarily to intracytoplasmic sperm injection.
Antenatal Steroids After 34 Weeks: Leaning Toward Harm
Women's Health
Summary and Comment
In utero corticosteroid exposure did not reduce respiratory morbidity but did raise risk for neonatal hypoglycemia and sepsis evaluation.
Prenatal Antipsychotics Affect Motor Performance in 6-Month-Olds
Psychiatry
Summary and Comment
Lingering deficits at 6 months support caution in prescribing antipsychotics during pregnancy, especially for nonpsychotic disorders.
By Barbara Geller, MD
April 30, 2012
Covering:
Johnson KC et al., Arch Gen Psychiatry 2012 Apr 2
Prenatal PPI Exposure and Childhood Asthma
Gastroenterology
Summary and Comment
Maternal PPI use during pregnancy or the year thereafter is associated with an increased risk for asthma in the offspring but may not be causal.
Poor Performance on Rh Immunoglobulin Use
Emergency Medicine
Summary and Comment
Only 56% of Rh-negative pregnant women with sensitizing events were treated appropriately at a single academic emergency department.
Pregnancy Complications as an Omen for Cardiovascular Disease
Women's Health
Summary and Comment
Free
Women who delivered small-for-gestational-age babies were more likely to experience ischemic heart disease in later life.
Ring Around the Cervix: Preventing Preterm Birth
Women's Health
Summary and Comment
Cervical pessary placement in women with short cervix was associated with lower risk for preterm delivery.
By Allison Bryant, MD, MPH
April 19, 2012
Covering:
Goya M et al., Lancet 2012 Apr 3
Caritis SN and Simhan H., Lancet 2012 Apr 3
Anticoagulation for Pregnant Women with Mechanical Prosthetic Heart Valves
Women's Health
Summary and Comment
Encouraging results with low-dose warfarin throughout pregnancy, but the approach must be validated.
By Kirsten E. Fleischmann, MD, MPH
April 19, 2012
Covering:
De Santo LS et al., J Am Coll Cardiol 2012 Mar 20; 59:1110
Elkayam U and Goland S., J Am Coll Cardiol 2012 Mar 20; 59:1116
Use of Boosted Protease Inhibitors in Pregnancy Linked to Prematurity
Another European study adds to the concern.
By Keith Henry, MD
April 13, 2012
Covering:
Sibiude J et al., Clin Infect Dis 2012 May 1; 54:1348
Tools for Preventing Postpartum Psychosis and Mania
Psychiatry
Summary and Comment
Free
Intrapartum lithium helps to minimize bipolar episodes, and postpartum lithium and sleep hygiene help to avoid postpartum psychosis.
By Joel Yager, MD
April 9, 2012
Covering:
Bergink V et al., Am J Psychiatry 2012 Mar 8
How Fast Is Fast Enough? Decision-to-Delivery Time in Uterine Rupture
Women's Health
Summary and Comment
Free
Better neonatal outcomes resulted when cesarean delivery occurred within 18 minutes of suspected uterine rupture.
Postpartum IUD Placement Is on the Rise but Still Lags Behind Sterilization
Women's Health
Summary and Comment
For every intrauterine device placed shortly after delivery, thousands of U.S. women still undergo postpartum sterilization.
Vaginal Progesterone Use in Pregnant Women with Short Cervix
Women's Health
Summary and Comment
Treatment with vaginal progesterone significantly reduced rates of preterm birth in women with short cervix with or without prior preterm delivery.
Does High HbA1c During Pregnancy Predict Postpartum Glucose Abnormalities?
Women's Health
Summary and Comment
Patients with highest HbA1c at diagnosis of gestational diabetes mellitus were more likely to develop abnormal glucose tolerance after delivery.