CIN Treatment and Preterm Birth: Revisiting the Association
Women's Health
Summary and Comment
Free
British study indicates that quality-assured treatment for cervical intraepithelial neoplasia does not raise obstetric risk.
OB/GYN Hospitalists: Emerging Trend or Sustainable Model?
Women's Health
Summary and Comment
Free
The role has both advantages and challenges.
Bringing Depression in Reproductive-Aged Women out of the Shadows
Women's Health
Summary and Comment
Among the 10% of pregnant and nonpregnant women who reported symptoms of a past-year major depressive episode, the disorder was undiagnosed in almost 60%.
Management of Thyroid Disease During and After Pregnancy
Women's Health
Clinical Practice Guideline Watch
Free
Updated guidelines explicitly address several issues related to thyroid dysfunction and pregnancy.
By Robert W. Rebar, MD
August 30, 2012
Covering:
De Groot L et al., J Clin Endocrinol Metab 2012 Aug; 97:2543
Revised DHHS Guidelines for Perinatal Antiretroviral Use
HIV/AIDS Clinical Care
Clinical Practice Guideline Watch
Free
The new guidelines offer more treatment options for pregnant HIV-infected women and explore the range of options available for safe conception in HIV-serodiscordant couples.
By Sally Hodder, MD
August 30, 2012
Covering:
Panel on Treatment of HIV-Infected Pregnant Women and Prevention of Perinatal Transmission., 2012 Jul 31
Birth Control Saves Women's Lives
Women's Health
Summary and Comment
Free
Meeting the global need for contraception could cut maternal mortality by an additional 29%.
Postcesarean Intrauterine Contraception
Women's Health
Summary and Comment
IUD placement immediately after cesarean delivery was well tolerated, with low likelihood of expulsion.
Noninvasive Fetal RHD Determination
Women's Health
Summary and Comment
Genotyping free fetal DNA in maternal blood is highly accurate and could help avert routine antenatal prophylaxis in RhD-negative women.
By Allison Bryant, MD, MPH
August 16, 2012
Covering:
Wikman AT et al., Obstet Gynecol 2012 Aug; 120:227
Queenan JT., Obstet Gynecol 2012 Aug; 120:219
Antenatal Stroke: What Do We Know About This Uncommon Event?
Women's Health
Summary and Comment
Histories of migraine, gestational diabetes, and hypertensive disorders are major risk factors.
Recognizing and Managing Postpartum Depression in the Trenches
Women's Health
Summary and Comment
Free
Practice-based intervention was associated with reduction in depressive symptoms in women as late as 1 year postpartum.
Transfers Out of Birthing Centers: Rates and Reasons
Women's Health
Summary and Comment
Large English study confirms 25% transfer rate; most common reason was failure to progress in labor.
Women's Predictions about Coping after Pregnancy Termination
Women's Health
Summary and Comment
Demographic and medical factors, as well as women's attitudes about abortion, affected their likelihood of anticipating difficulty coping after the procedure.
Valproate Exposure In Utero Can Affect Cognitive Outcomes
Women's Health
Summary and Comment
Children exposed to valproate had lower IQs at age 4.5 years than did children exposed to other AEDs.
Obesity's Effects on Duration of Labor
Women's Health
Summary and Comment
Obese women took longer to progress from 4-cm to 6-cm cervical dilation.
Women Who Seek Second-Trimester Abortions
Women's Health
Summary and Comment
Those who are younger, black, or less educated are more likely to terminate pregnancies after 12 weeks' gestation.
Eating for Two in the Obesity Era
Women's Health
Summary and Comment
Dietary interventions during pregnancy curbed maternal weight gain.
Deinfibulation During Delivery
Women's Health
Summary and Comment
Intrapartum cutting of the infibulation scar appears safe and well tolerated.
By Anna Wald, MD, MPH
July 12, 2012
Covering:
Rouzi AA et al., Obstet Gynecol 2012 Jul; 120:98
Does Vaginal Lubricant Impede Procreation?
Women's Health
Summary and Comment
U.S. study suggests that lubricant does not reduce fertility.
Combination Infant Prophylaxis Reduces HIV Transmission after Late Maternal Diagnosis
Use of combination therapy rather than AZT monotherapy cut the rate of intrapartum HIV transmission in half.
By Holly E. Rawizza, MD
July 9, 2012
Covering:
Nielsen-Saines K et al., N Engl J Med 2012 Jun 21; 366:2368
Metformin for Antipsychotic-Induced Adverse Effects in Women with Schizophrenia
Psychiatry
Summary and Comment
Free
The medication reversed amenorrhea, promoted weight loss, and improved insulin resistance.
By Joel Yager, MD
July 9, 2012
Covering:
Wu R-R et al., Am J Psychiatry 2012 Jun 15
Triple-Drug ART for MTCT Prevention: Safe for Moms, Too
The risk for HIV disease progression was not elevated in women who received a limited course of triple-drug ART for MTCT prophylaxis, compared with women who received shorter-course prophylaxis containing fewer drugs.
Antidepressants Linked to Shorter Gestation and Neonatal Seizures
Psychiatry
Summary and Comment
In a large population, most women stopped antidepressants in pregnancy, but their continued use increased neonatal risks.
By Deborah Cowley, MD
July 2, 2012
Covering:
Hayes RM et al., Am J Obstet Gynecol 2012 Jul; 207:49.e1
Fetal Safety of Newer Antiepileptic Drugs During Pregnancy
Women's Health
Summary and Comment
Risk for major congenital malformations is low for most AEDs, although newer AEDs are not necessarily safer than older ones.
Assisted Reproductive Technology: Cumulative Live-Birth Rates Offer Hope to Infertile Couples
Women's Health
Summary and Comment
Free
Cumulative live-birth rates can approach those arising from spontaneous conception.
By Robert W. Rebar, MD
June 27, 2012
Covering:
Luke B et al., N Engl J Med 2012 Jun 28; 366:2483
Briefly Noted
Therapy for pustular psoriasis, rituximab-related psoriasis flare, methotrexate for children with localized scleroderma, methotrexate for skin lesions in dermatomyositis, treatment of non–infection-related cryoglobulinemic vasculitis, and hydroxychloroquine to prevent congenital heart block