Screening for Down Syndrome: Nasal Bones
Women's Health
Summary and Comment
Ultrasound assessment of fetal nasal bones improves prenatal detection of Down syndrome.
By Sandra Ann Carson, MD
August 17, 2006
Covering:
Cicero S et al., Am J Obstet Gynecol 2006 Jul; 195:109-14
Is Aspirin Use Related to Early Pregnancy Loss?
Women's Health
Summary and Comment
Old data indicate that the answer is no.
By Diane E. Judge, APN/CNP
August 10, 2006
Covering:
Keim SA and Klebanoff MA., Epidemiology 2006 Jul; 17:435-9
ACE Inhibitors Increase Risk for Congenital Anomalies in the First Trimester, Too
The risk more than doubled.
By Howard Bauchner, MD
August 9, 2006
Covering:
Cooper WO et al., N Engl J Med 2006 Jun 8; 354:2443-51
Sperm Washing for Serodiscordant Couples Who Want a Child
HIV/AIDS Clinical Care
Antiretroviral Rounds
Experts describe the basics of sperm washing and weigh the risks of assisted reproduction against those from unprotected intercourse to achieve pregnancy.
By Elizabeth Jenny-Avital, MD, Carole Gilling-Smith, MA, FRCOG, PhD, and Lori Panther, MD, MPH
August 7, 2006
Early Menopause in Childhood Cancer Survivors
Women's Health
Summary and Comment
Premature menopause is a long-term consequence of treatment of childhood cancer.
By Andrew M. Kaunitz, MD
August 3, 2006
Covering:
Sklar CA et al., J Natl Cancer Inst 2006 Jul 5; 98:890-6
Risks of Romantic Involvement by the 7th Grade
Having a boyfriend by 7th grade predicts sexual activity by 9th grade.
By Alain Joffe, MD, MPH
August 2, 2006
Covering:
Marin BV et al., Perspect Sex Reprod Health 2006 Jun; 38:76-83
Greatest Risk Factor for Ectopic Pregnancy: Previous Ectopic Pregnancy
General Medicine
Summary and Comment
Women with ectopic pregnancies were three times as likely as controls to have had previous ectopic pregnancies; multiple prior ectopic pregnancies raised risk even further.
By Robert W. Rebar, MD
July 27, 2006
Covering:
Barnhart KT et al., Fertil Steril 2006 Jul; 86:36-43
Vitamins C and E and the Risk for Preeclampsia and Perinatal Complications
Women's Health
Summary and Comment
Neither mothers, nor their infants, benefited from maternal vitamin C and E supplementation during pregnancy.
By Sandra Ann Carson, MD
July 20, 2006
Covering:
Rumbold AR et al., N Engl J Med 2006 Apr 27; 354:1796-806
ACE Inhibitors and Birth Defects: Unsafe in Any Trimester
Women's Health
Summary and Comment
Free
Treatment with ACE inhibitors increases risk for major malformations when used in the first trimester as well as later in pregnancy.
By Andrew M. Kaunitz, MD
July 13, 2006
Covering:
Cooper WO et al., N Engl J Med 2006 Jun 8; 354:2443-51
Friedman JM., N Engl J Med 2006 Jun 8; 354:2498-500
Sex Is for Starting a Pregnancy, Not Finishing It
Women's Health
Summary and Comment
Sexual activity at term does not hasten the onset of labor.
By Sandra Ann Carson, MD
July 13, 2006
Covering:
Schaffir J., Obstet Gynecol 2006 Jun; 107:1310-4
Maternal Morbidity Increases with Recurrent Cesarean Delivery
Women's Health
Summary and Comment
Women undergoing repeat cesarean delivery are at increased risk for serious complications, including placenta accreta and hysterectomy.
By Sandra Ann Carson, MD
July 13, 2006
Covering:
Silver RM et al., Obstet Gynecol 2006 Jun; 107:1226-32
Scott JR., Obstet Gynecol 2006 Jun; 107:1222-3
Female Genital Cutting and Obstetric Risk
Women's Health
Summary and Comment
Female genital cutting is associated with increased risk for various adverse maternal and neonatal outcomes.
By Anna Wald, MD, MPH
July 13, 2006
Covering:
Lancet 2006 Jun 3; 367:1835-41
Eke N and Nkanginieme KEO., Lancet 2006 Jun 3; 367:1799-800
Is Surgical Management Required After Miscarriage?
General Medicine
Summary and Comment
Expectant management might be appropriate for very early incomplete miscarriage, but as many as 30% of expectantly managed patients require emergency admission.
By Robert W. Rebar, MD
July 11, 2006
Covering:
Trinder J et al., BMJ 2006 May 27; 332:1235-40
Weeks A and Danielsson KG., BMJ 2006 May 27; 332:1223-4
Weekly Maternal Steroids Can Reduce RDS in Preterm Neonates
General Medicine
Summary and Comment
Rates of neonatal respiratory distress syndrome were lower when steroids were given, with no indication of other adverse outcomes.
By Bruce Soloway, MD
July 11, 2006
Covering:
Crowther CA et al., Lancet 2006 Jun 10; 367:1913-9
Montan S and Arulkumaran S., Lancet 2006 Jun 10; 367:1878-9
Adverse Neonatal Outcomes After Female Genital Mutilation
General Medicine
Summary and Comment
Likelihood of adverse outcomes increased with the severity of mutilation.
By Bruce Soloway, MD
July 11, 2006
Covering:
WHO study group on female genital mutilation and obstetric outcome., Lancet 2006 Jun 3; 367:1835-41
Eke N and Nkanginieme KEO., Lancet 2006 Jun 3; 367:1799-800
Male Hormonal Contraception
Women's Health
Summary and Comment
Men who use androgen therapy can expect full sperm recovery within 24 months of treatment cessation.
By Sandra Ann Carson, MD
June 30, 2006
Covering:
Liu PY et al., Lancet 2006 Apr 29; 367:1412-20
Can One Semen Analysis Confirm Vasectomy Success?
Women's Health
Summary and Comment
Reducing the number of semen analyses to one may boost adherence without compromising accuracy.
By Diane E. Judge, APN/CNP
June 20, 2006
Covering:
Dhar NB et al., BJU Int 2006 Apr; 97:773-6
Folate Levels and Multiple Births Following IVF
Women's Health
Summary and Comment
Increased folate intake and levels are associated with a greater likelihood of twinning in women undergoing in vitro fertilization.
By Anna Wald, MD, MPH
June 30, 2006
Covering:
Haggarty P et al., Lancet 2006 May 6; 367:1513-9
Steinman G., Lancet 2006 May 6; 367:1461-2
Predicting Which Tubal Sterilization Candidates Will Request Reversal
Women's Health
Summary and Comment
A study of U.S. military beneficiaries who have undergone tubal sterilization offers insight.
By Andrew M. Kaunitz, MD
June 20, 2006
Covering:
Moseman CP et al., Contraception 2006 May; 73:512-5
Cesarean Delivery Increases Subsequent Risk for Previa and Abruption
Women's Health
Summary and Comment
Free
Women with previous cesarean deliveries are at increased risk for previa and abruption in their second and third pregnancies.
By Sandra Ann Carson, MD
June 20, 2006
Covering:
Getahun D et al., Obstet Gynecol 2006 Apr; 107:771-8
Infertility, Rather Than Its Treatment, Is Associated with Perinatal Morbidity
Women's Health
Summary and Comment
In this twin study, ART pregnancies had a higher risk for premature and low birth weight infants.
By Sandra Ann Carson, MD
June 30, 2006
Covering:
Ombelet W et al., Hum Reprod 2006 Apr; 21:1025-32
Parity Increases Sexual Dysfunction
Women's Health
Summary and Comment
Childbirth had long-term negative effects on sexual satisfaction in this study of identical twins.
By Sandra Ann Carson, MD
June 20, 2006
Covering:
Botros SM et al., Obstet Gynecol 2006 Apr; 107:765-70
When Women with Turner Syndrome Receive Oocyte Donation
Women's Health
Summary and Comment
Patients with Turner syndrome who received oocyte donation had a 40% clinical pregnancy rate.
By Sandra Ann Carson, MD
June 30, 2006
Covering:
Bodri D et al., Hum Reprod 2006 Mar; 21:829-32
Obstetric Risks of Protease Inhibitors During Pregnancy
Women's Health
Summary and Comment
Combination therapy including a protease inhibitor during pregnancy increased the risk for preterm delivery.
By Anna Wald, MD, MPH
June 6, 2006
Covering:
Cotter AM et al., J Infect Dis 2006 May 1; 193:1195-201
Tuomala RE and Yawetz S., J Infect Dis 2006 May 1; 193:1191-4
Fragile X Screening Likely to Be Requested by Patients
Women's Health
Summary and Comment
When asked, many women with ovarian dysfunction wanted to be tested for fragile X "premutation."
By Sandra Ann Carson, MD
June 6, 2006
Covering:
Pastore LM et al., Am J Obstet Gynecol 2006 Mar; 194:738-43