What Do Obstetrician/Gynecologists Think About Assisted Reproductive Technologies?
Women's Health
Summary and Comment
Free
Fewer than 5% of respondents had moral or ethical objections to ART or in vitro fertilization, but reactions to hypothetical scenarios varied widely.
By Ann J. Davis, MD
July 22, 2010
Covering:
Lawrence RE et al., Obstet Gynecol 2010 Jul; 116:127
Modern Management of Miscarriage: How Up-to-Date Are We?
Women's Health
Summary and Comment
Survey results indicate that office uterine evacuation and misoprostol are much underutilized.
Updated Guidelines for Perinatal Antiretroviral Use
HIV/AIDS Clinical Care
Clinical Practice Guideline Watch
The panel reaffirms its clinical recommendations, using a new rating system.
By Sally Hodder, MD
July 12, 2010
Covering:
Panel on Treatment of HIV-Infected Pregnant Women and Prevention of Perinatal Transmission., 2010 May 24
Super-Obesity Foreshadows Preeclampsia
Women's Health
Summary and Comment
Free
Risk for preeclampsia rose with prepregnancy body-mass index and rate of weight gain during pregnancy.
Consequences of Substandard Care During Labor
Women's Health
Summary and Comment
An estimated 42% of low Apgar scores could have been prevented if substandard care had been avoided.
Early-Onset Preeclampsia in First Pregnancies Predicts Complications in Normotensive Second Pregnancies
Women's Health
Summary and Comment
Primigravidas with early-onset preeclampsia were at excess risk for small-for-gestational-age infants, premature birth, and placental abruption in second normotensive pregnancies.
Probiotics to Treat Patients with Mastitis
General Medicine
Summary and Comment
Lactobacilli held their own against antibiotics . . . but how?
By Abigail Zuger, MD
June 22, 2010
Covering:
Arroyo R et al., Clin Infect Dis 2010 Jun 15; 50:1551
Levonorgestrel Emergency Contraception Works Before and Not After Fertilization
Women's Health
Summary and Comment
Free
Pregnancy was prevented when LNG EC was administered before ovulation but not on the day of ovulation or thereafter.
Which Older Women Skip Contraception Despite Not Wanting Pregnancy?
Women's Health
Summary and Comment
Women who were older, black, or born outside the U.S. were less likely to use contraception, even though they did not desire pregnancy.
Preventing Mother-to-Infant HIV Transmission
Infectious Diseases
Summary and Comment
Free
In two large, randomized studies conducted in sub-Saharan Africa, antiretroviral regimens given to lactating mothers or their infants reduced postnatal HIV acquisition.
By Rajesh T. Gandhi, MD
June 16, 2010
Covering:
Shapiro RL et al., N Engl J Med 2010 Jun 17; 362:2282
Chasela CS et al., N Engl J Med 2010 Jun 17; 362:2271
Mofenson LM., N Engl J Med 2010 Jun 17; 362:2316
Quick Herpes Test for Women in Labor to Help Prevent Transmission to Newborns
Women's Health
Summary and Comment
Rapid testing for HSV in vaginal specimens from laboring women had very high sensitivity and specificity.
By Wendy S. Biggs, MD
June 10, 2010
Covering:
Gardella C et al., Obstet Gynecol 2010 Jun; 115:1209
When Pregnancy Is Forced
Women's Health
Summary and Comment
Pregnancy coercion and birth-control sabotage were reported by 19% and 15% of women surveyed at family planning clinics.
Providing Parental Advice When Extremely Premature Birth Is Inevitable
Women's Health
Summary and Comment
Free
Caregivers and parents have different preferences about information and support given in association with periviable delivery.
First-Trimester Vaginal Bleeding as a Marker of Unfavorable Pregnancy Outcomes
Women's Health
Summary and Comment
Bleeding early during pregnancy was associated with complications in current and future pregnancies.
Excessive Nausea and Vomiting During Early Pregnancy Runs in Families
Women's Health
Summary and Comment
Women whose mothers experienced hyperemesis gravidarum were at threefold excess risk for the condition themselves.
Metoclopramide vs. Promethazine for Hyperemesis Gravidarum
Women's Health
Summary and Comment
Both agents were effective, but promethazine had more adverse effects — and has a black box warning.
By Wendy S. Biggs, MD
May 27, 2010
Covering:
Tan PC et al., Obstet Gynecol 2010 May; 115:975
Cutaneous Neonatal Lupus Erythematosus and Risk for Heart Block in Subsequent Pregnancy
Dermatology
Summary and Comment
Exposure to maternal anti-Ro/SS-A autoantibodies increases the risk for fetal or neonatal heart block.
IVIG Does Not Prevent Neonatal Lupus Erythematosus–Associated Heart Block
Dermatology
Summary and Comment
Intravenous immune globulin had no effect on maternal antibody levels or on incidence of congenital heart block.
By Jeffrey P. Callen, MD
May 14, 2010
Covering:
Pisoni CN et al., Arthritis Rheum 2010 Apr; 62:1147
Friedman DM et al., Arthritis Rheum 2010 Apr; 62:1138
stensen M., Arthritis Rheum 2010 Apr; 62:911
Maternal Dietary Vitamin A Is Crucial for Fetal Lung Development
Women's Health
Summary and Comment
In a population with chronic vitamin A deficiency, maternal supplementation before, during, and after pregnancy improved offsprings' lung function.
By Wendy S. Biggs, MD
May 13, 2010
Covering:
Checkley W et al., N Engl J Med 2010 May 13; 362:1784
Massaro D and Massaro GD., N Engl J Med 2010 May 13; 362:1829
Bariatric Surgery Is Associated with Lower Rates of Hypertensive Disorders in Pregnancy
General Medicine
Summary and Comment
Obese women who underwent surgery before pregnancy had fewer perinatal complications than obese women who had surgery after giving birth.
Bariatric Surgery Brings Benefits: Lower Risk for Hypertensive Disorders in Pregnancy
Women's Health
Summary and Comment
Free
Bariatric surgery prior to pregnancy was associated with lower risk for preeclampsia and other hypertensive disorders.
Protease Inhibitors and Prematurity
A large study finds no significant risk for preterm birth from PI use during pregnancy.
By Abigail Zuger, MD
May 3, 2010
Covering:
Patel K et al., J Infect Dis 2010 Apr 1; 201:1035
Kourtis AP., J Infect Dis 2010 Apr 1; 201:978
Antiviral Treatment for Influenza During Pregnancy
Women's Health
Summary and Comment
Treatment was not associated with adverse neonatal or maternal outcomes.
By Anna Wald, MD, MPH
April 29, 2010
Covering:
Greer LG et al., Obstet Gynecol 2010 Apr; 115:711
Pandemic 2009 H1N1 Influenza During Pregnancy
Infectious Diseases
Summary and Comment
Free
Such illness was associated with significant morbidity and mortality; early antiviral treatment was beneficial.
Aspirin (Alone or with Heparin) for Unexplained Recurrent Miscarriage?
Women's Health
Summary and Comment
Free
Neither treatment helped.
By Robert W. Rebar, MD
April 22, 2010
Covering:
Kaandorp SP et al., N Engl J Med 2010 Apr 29; 362:1586
Greer IA., N Engl J Med 2010 Apr 29; 362:1630