Henoch-Schönlein Purpura After Influenza Vaccination
This complication is rare and self-limited in most instances.
Treatment Failure in Children with HIV
HIV/AIDS Clinical Care Summary and Comment
Free
Although the rate of triple-class virologic failure was low among children, it was more than twice that seen in adults.
By Holly Rawizza, MD
May 9, 2011
Covering:
The Pursuing Later Treatment Options II (PLATO II) project team for the Collaboration of Observational HIV Epidemiological Research Europe (COHERE)., Lancet 2011 May 7/13; 377:1580
FDA Approves Conjugate Meningococcal Vaccine for Younger Children
Infectious Diseases Vaccine Watch
Free
A tetravalent conjugate meningococcal vaccine (Menactra) is now approved for infants as young as 9 months.
Delaying Antibiotics in Pediatric Pneumonia Increases Morbidity
Emergency Medicine Summary and Comment
Delays in antibiotic administration for critically ill children with pneumonia resulted in longer duration of mechanical ventilation and longer hospital stays.
By Katherine Bakes, MD
April 29, 2011
Covering:
Muszynski JA et al., Pediatr Infect Dis J 2011 Apr; 30:295
Bacteria Are an Uncommon Cause of Pediatric Epididymitis
Emergency Medicine Summary and Comment
Antibiotics rarely are indicated for pediatric epididymitis.
By Katherine Bakes, MD
April 22, 2011
Covering:
Santillanes G et al., Pediatr Emerg Care 2011 Mar; 27:174
Classic Clinical Indicators of Meningitis in Children Have Limited Diagnostic Utility
Emergency Medicine Summary and Comment
. . . but, they might help identify patients with bacterial etiologies.
By Katherine Bakes, MD
April 15, 2011
Covering:
Amarilyo G et al., Pediatr Emerg Care 2011 Mar; 27:196
Dexamethasone Speeds Recovery in Pediatric Septic Arthritis
A randomized study confirms a benefit from corticosteroid treatment.
Complications of Sinusitis in Children
Infectious Diseases Summary and Comment
Intracranial complications were more severe than intraorbital complications.
Cephalexin vs. Clindamycin in Children with Skin Infections
Outcomes were similar with the two drugs, but most children with uncomplicated skin abscesses can be treated with incision and drainage alone.
Propranolol for Ulcerated Infantile Hemangiomas
Dermatology Summary and Comment
Propranolol was effective in 33 infants with problematic ulcerated hemangiomas.
By Mary Wu Chang, MD
March 25, 2011
Covering:
Saint-Jean M et al., J Am Acad Dermatol 2011 Feb 24
Harlequin Ichthyosis: Management and Long-Term Outcomes
Dermatology Summary and Comment
Clinical and molecular findings in infants with harlequin ichthyosis; early retinoid therapy helps.
Decreasing Central Line–Associated Infections in the NICU
Infectious Diseases Summary and Comment
At 18 neonatal intensive care units in New York State, infection rates dropped significantly after implementation of standardized, evidence-based central line insertion and maintenance bundles.
By Robert S. Baltimore, MD
March 16, 2011
Covering:
Schulman J et al., Pediatrics 2011 Mar; 127:436
Kaplan HC et al., Pediatrics 2011 Mar; 127:427
Wirtschafter DD et al., Pediatrics 2011 Mar; 127:419
Do Topical Antibiotics Promote Wound Healing in the Absence of Infection?
Dermatology Summary and Comment
Three small studies found that a petrolatum-based ointment advanced wound healing as well as topical antibiotics.
By Jan V. Hirschmann, MD
March 11, 2011
Covering:
Taylor SC et al., J Am Acad Dermatol 2011 Mar; 64:S30
Draelos ZD et al., J Am Acad Dermatol 2011 Mar; 64:S23
Trookman NS et al., J Am Acad Dermatol 2011 Mar; 64:S8
Simple Febrile Seizures: A New Guideline
Pediatrics and Adolescent Medicine Clinical Practice Guideline Watch
An updated practice parameter on neurodiagnostic evaluation
By Howard Bauchner, MD
March 9, 2011
Covering:
Subcommittee on Febrile Seizures., Pediatrics 2011 Feb; 127:389
Guidelines for Pre- and Peritonsillectomy Decisions
Pediatrics and Adolescent Medicine Clinical Practice Guideline Watch
A useful guide for making decisions about referral for tonsillectomy
By Peggy Sue Weintrub, MD
February 23, 2011
Covering:
Baugh RF et al., Otolaryngol Head Neck Surg 2010 Dec 31; 144:S1
Antibody Titers in Infants Born to HIV-Positive Women
Infectious Diseases Summary and Comment
Free
HIV-exposed but uninfected newborns had decreased antibody levels to vaccine-preventable diseases.
A 10-Year Look at C. difficile Infection in U.S. Hospitalized Children
<$EMPH_O>Clostrdium difficile<$EMPH_C> infection is becoming more common but not more severe.
Association Between Enterovirus Infection and Type 1 Diabetes
General Medicine Summary and Comment
The clinically significant link probably involves viruses, pancreatic islet cells, and patients' immune systems and genotypes.
By Paul S. Mueller, MD, MPH, FACP
February 15, 2011
Covering:
Yeung W-CG et al., BMJ 2011 Feb 3; 342:d35
Hober D and Sane F., BMJ 2011 Feb 3; 342:c7072
Starting and Switching Antiretroviral Therapy in Children
First-line PI- and NNRTI-based therapies offer equivalent virologic efficacy in children without prior exposure to NNRTIs. However, when failure occurs, an immediate switch is necessary for those on NNRTIs.
By Holly Rawizza, MD
February 14, 2011
Covering:
The PENPACT-1. (PENTA 9/PACTG 390) Study Team., Lancet Infect Dis 2011 Feb 1
Spinosad Now FDA Approved for Treating Head Lice
In two phase III trials, spinosad was significantly more effective than 1% permethrin.
Treatment of Acute Otitis Media in Infants and Young Children
Do these two studies end the debate?
By Howard Bauchner, MD , and Peggy Sue Weintrub, MD
February 2, 2011
Covering:
Tähtinen PA et al., N Engl J Med 2011 Jan 13; 364:116
Hoberman A et al., N Engl J Med 2011 Jan 13; 364:105
Klein JO., N Engl J Med 2011 Jan 13; 364:168
Steroids for Children with Community-Acquired Pneumonia?
Infectious Diseases Summary and Comment
Hospital length of stay was shorter in children who received corticosteroids — but only in those with wheezing.
A Better Way of Screening TB Contacts
General Medicine Summary and Comment
An interferon-
By Abigail Zuger, MD
February 1, 2011
Covering:
Diel R et al., Am J Respir Crit Care Med 2011 Jan 1; 183:88
Lange C and Rieder HL., Am J Respir Crit Care Med 2011 Jan 1; 183:3
CDC Releases New Guidelines for Perinatal Group B Streptococcal Disease
Women's Health Clinical Practice Guideline Watch
Updates to the 2002 prevention guidelines provide more clarity for clinicians.
Predicting Respiratory Syncytial Virus Infections in Healthy Infants
Infectious Diseases Summary and Comment
Four risk factors were identified; infants with all four had a 32% chance of RSV lower respiratory tract infection during the first year of life.
