Does Early Otitis Media Lead to IBD?
Another potential long-term consequence of indiscriminate antibiotic use
Topical Ivermectin Lotion for the Treatment of Head Lice
Dermatology
Summary and Comment
Free
One 10-minute application was very effective and could help avoid systemic medication.
By Mary Wu Chang, MD
October 31, 2012
Covering:
Pariser DM et al., N Engl J Med 2012 Nov 1; 367:1687
Eczema Herpeticum in Children: Predictors of Hospitalization
Dermatology
Summary and Comment
The danger of recurrence makes it important to control atopic dermatitis and recognize the signs of eczema herpeticum.
By Mary Wu Chang, MD
October 12, 2012
Covering:
Luca NJC et al., J Pediatr 2012 Oct; 161:671
Pediatric Mortality Risk During the H1N1 Pandemic Flu Season
Underlying neurologic disease is associated with mortality.
Can CLABSI Rates Be Reduced in Pediatric Oncology Patients?
Infectious Diseases
Summary and Comment
Implementation of a central-line maintenance care bundle resulted in reductions of 20% to 64%, but the decreases were not statistically significant.
Is Early Antibiotic Exposure Associated with Increases in Body Mass?
Exposure during the first 6 months of life was associated with increased body mass at ages 10 to 38 months, but the effect disappeared by age 7 years.
Pediatric-Specific Antibiotic Susceptibilities Differ from Adult Antibiograms
Knowledge of pediatric-specific antibiotic susceptibilities could improve our ability to choose appropriate empiric antibiotics for childhood infections.
By Louis M. Bell, MD
September 26, 2012
Covering:
Boggan JC et al., Pediatrics 2012 Sep; 130:e615
Inflammatory Reactions of Molluscum Contagiosum in Children
Dermatology
Summary and Comment
Free
Inflammatory reactions are common in this self-limited viral skin infection.
By Mary Wu Chang, MD
September 21, 2012
Covering:
Berger EM et al., Arch Dermatol 2012 Aug 20
Protection From Acellular Pertussis Vaccine Wanes After 5 Years
Risk for pertussis increased 42% each year after the fifth dose of DTaP.
Wet Wrap ASAP
Dermatology
Summary and Comment
Free
An underused, intensive topical treatment is effective for severe atopic dermatitis.
By Mark V. Dahl, MD
September 7, 2012
Covering:
Dabade TS et al., J Am Acad Dermatol 2012 Jul; 67:100
Five-Year Outcomes in Children with Documented Lyme Neuroborreliosis
Most children had full recovery, and 25% had persistent symptoms; nonspecific symptoms were not related to the infection.
Trends in HIV Risk Behaviors in Teens from 1991 to 2011
Improvements in the first decade are now dangerously stalled.
By Peggy Sue Weintrub, MD
August 15, 2012
Covering:
Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2012 Jul 27; 61:556
Honey Helps Kids with Nocturnal Cough
Honey is worth a try in children older than 1 year.
Does Prompt Antifungal Treatment Improve Outcomes in Tiny Neonates?
Infectious Diseases
Summary and Comment
Among premature infants with invasive candidiasis, receipt of empirical antifungal therapy was associated with a lower rate of death or neurodevelopmental impairment.
Pertussis on the Rise
Infectious Diseases
Summary and Comment
Free
Pertussis reached epidemic proportions in Washington State in 2012, apparently because of waning immunity in individuals who received acellular vaccines during childhood.
By Stephen G. Baum, MD
August 1, 2012
Covering:
Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2012 Jul 20; 61:517
Does Dog or Cat Exposure Protect Against Respiratory Tract Infections During the First Year of Life?
In this prospective study, dog contact was more protective than cat contact, but the results leave the question unresolved.
Outbreak of Illness and Death Among Children in Cambodia
Infectious Diseases
News in Context
Free
The outbreak appears to have been caused by enterovirus 71.
Good News About Antibiotic Use in Children, but Judicious Use Is Still Needed
From 2000–2005, the decline in antibiotic dispensing rates for children in Massachusetts was largely attributable to lower rates of otitis media diagnoses, but the decline has stalled.
By Louis M. Bell, MD
July 11, 2012
Covering:
Greene SK et al., Pediatrics 2012 Jul; 130:15
Initial Bone and Joint Cultures Improve Outpatient Management of Musculoskeletal Infection
Cultures from the infection site were twice as likely as blood cultures to identify the causative organism, and identification of the causative pathogen was associated with discharge on a single oral antibiotic.
Low Risk for Urinary Tract Infection After Endoscopic Treatment of Vesicoureteral Reflux
Endoscopic correction of intermediate or high-grade VUR is less invasive than surgical correction and reduces risk for subsequent febrile UTI.
Antibiotics Are Associated with Elevated Risk for Hemolytic Uremic Syndrome
General Medicine
Summary and Comment
However, confounding by severity of illness might have influenced the findings.
By Abigail Zuger, MD
July 10, 2012
Covering:
Wong CS et al., Clin Infect Dis 2012 Jul 1; 55:33
Lopinavir/Ritonavir Superior for Young Children
Among young children with no prior NNRTI exposure, treatment failure was significantly less common with lopinavir/ritonavir than with nevirapine.
By Holly E. Rawizza, MD
July 9, 2012
Covering:
Violari A et al., N Engl J Med 2012 Jun 21; 366:2380
Combination Infant Prophylaxis Reduces HIV Transmission after Late Maternal Diagnosis
Use of combination therapy rather than AZT monotherapy cut the rate of intrapartum HIV transmission in half.
By Holly E. Rawizza, MD
July 9, 2012
Covering:
Nielsen-Saines K et al., N Engl J Med 2012 Jun 21; 366:2368
Rash Decisions: Atypical Exanthems in 260 Consecutive Patients
Dermatology
Summary and Comment
Free
Awareness of morphologic pattern and of seasonal viruses may help with a difficult diagnosis.
By Mary Wu Chang, MD
June 22, 2012
Covering:
Drago F et al., J Am Acad Dermatol 2012 May 22
Imported Measles — An Ounce of Prevention ...
Infectious Diseases
Summary and Comment
Free
Immigration of an unvaccinated, measles-infected refugee from Burma resulted in three additional cases of measles and an investigation involving 298 contacts.
By Stephen G. Baum, MD
June 20, 2012
Covering:
Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2012 Jun 1; 61:385