Does Antibiotic Prophylaxis Prevent UTI Recurrence in Children?
General Medicine
Summary and Comment
Antibiotic prophylaxis doesnt prevent recurrent UTI or new renal scars.
By Howard Bauchner, MD
November 13, 2008
Covering:
Montini G et al., Pediatrics 2008 Nov; 122:1064
Its Always Time to Immunize
More than 80% of outpatient visits involving adolescents who were eligible to receive the Td vaccine were considered missed opportunities.
Exposure to Nontraditional Pets: Its a Jungle Out There
Exotic animals are not good pets!
Effect of Antibiotic Pretreatment in Children with Meningitis
Antibiotic treatment before lumbar puncture reduces the likelihood of a positive blood culture.
By Howard Bauchner, MD
October 22, 2008
Covering:
Nigrovic LE et al., Pediatrics 2008 Oct; 122:726
Oral Probiotics to Prevent Necrotizing Enterocolitis
Infectious Diseases
Summary and Comment
A mixture of <$EMPH_O>Lactobacillus acidophilu<$EMPH_C>s and <$EMPH_O>Bifidobacterium bifidum<$EMPH_C> lowered the incidence of necrotizing enterocolitis in very-low-birth-weight premature infants.
New Formulation of Combination Antimalarial Drug for Children
Infectious Diseases
Summary and Comment
Artemether-lumefantrine in a dispersible cherry-flavored tablet showed safety and efficacy profiles similar to those of crushed conventional tablets.
By Mary E. Wilson, MD
October 22, 2008
Covering:
Abdulla S et al., Lancet 2008 Oct 15
Teklehaimanot A and Teklehaimanot HD., Lancet 2008 Oct 15
Delivering Palivizumab at Home
General Medicine
Summary and Comment
Home administration resulted in better adherence and fewer hospitalizations for RSV infection.
By Howard Bauchner, MD
October 21, 2008
Covering:
Frogel M et al., Pediatr Infect Dis J 2008 Oct; 27:870
What Is the Best Treatment for Nontuberculous Mycobacterial Cervical Lymphadenitis?
General Medicine
Summary and Comment
NTM cervical lymphadenitis resolved in 6 to 12 months in 100% of 92 children who did not undergo lymph node excision.
By Howard Bauchner, MD
October 21, 2008
Covering:
Zeharia A et al., Pediatr Infect Dis J 2008 Oct; 27:920
Starke JR., Pediatr Infect Dis J 2008 Oct; 27:923
Cognitive-Behavioral Therapy for Depressed Mothers in Rural Pakistan
Psychiatry
Summary and Comment
Minimally trained rural health workers can make a difference.
Baby Steps Toward Polio Eradication
Infectious Diseases
Summary and Comment
Free
Monovalent type 1 oral poliovirus vaccine in children, including newborns, was more efficacious than conventional trivalent vaccine.
By Larry M. Baddour, MD
October 15, 2008
Covering:
El-Sayed N et al., N Engl J Med 2008 Oct 16; 359:1655
Jenkins HE et al., N Engl J Med 2008 Oct 16; 359:1666
Ehrenfeld E and Chumakov K., N Engl J Med 2008 Oct 16; 359:1726
Myth Shattered About Early Treatment for Acute Pyelonephritis in Children
Emergency Medicine
Summary and Comment
Early antibiotic treatment does not reduce renal scarring.
FDA Alert: TNF Blockers and Risk for Fungal Infections
The FDA now requires stronger warnings about risk for opportunistic fungal infections in patients treated with TNF blockers.
Comparison of Acetaminophen, Ibuprofen, and Both Agents for Treatment of Fever in Children
Acetaminophen plus ibuprofen and ibuprofen alone are equally effective in reducing fever.
By Robin Drucker, MD
October 1, 2008
Covering:
Hay AD et al., BMJ 2008 Sep 2; 337:a1302
Kawasaki Disease: Predicting Treatment Nonresponse
Infectious Diseases
Summary and Comment
Low albumin levels, high band counts, and abnormal initial echocardiography results were associated with poor response to IVIG treatment.
Acetaminophen and Asthma in Children
General Medicine
Summary and Comment
Retrospective results suggest a relation between acetaminophen use in infancy and development of asthma.
By Howard Bauchner, MD
September 25, 2008
Covering:
Beasley R et al., Lancet 2008 Sep 20; 372:1039
Barr RG., Lancet 2008 Sep 20; 372:1011
Novel Approach to Infant Influenza
Maternal influenza immunization reduced influenza illness in infants and respiratory illness with fever in infants and mothers.
Is Acetaminophen Use Linked to Asthma in Young Children?
The results of this retrospective study suggest an association but do not establish a causal relation.
By F. Bruder Stapleton, MD
September 24, 2008
Covering:
Beasley R et al., Lancet 2008 Sep 20; 372:1039
Barr RG., Lancet 2008 Sep 20; 372:1011
Maternal Influenza Immunization Protects Infants
Infectious Diseases
Summary and Comment
Free
Inactivated influenza vaccine reduced respiratory illness in the infants of women who were immunized during pregnancy.
Novel Approach to Infant Influenza
General Medicine
Summary and Comment
Influenza immunization during pregnancy attenuated influenza in infants and respiratory illness with fever in infants and in mothers.
Use of Ondansetron in Children with Gastroenteritis
The results of this meta-analysis strengthen the finding that ondansetron reduces the risk for vomiting in children with presumed gastroenteritis.
By Howard Bauchner, MD
September 17, 2008
Covering:
DeCamp LR et al., Arch Pediatr Adolesc Med 2008 Sep; 162:858
Early Antibiotic Treatment of Pyelonephritis
Early antibiotic treatment did not affect the rate of renal scarring compared with delayed treatment.
By Howard Bauchner, MD
September 17, 2008
Covering:
Hewitt IK et al., Pediatrics 2008 Sep; 122:486
Bronchoscopy for Diagnosing TB in Children
Infectious Diseases
Summary and Comment
Flexible bronchoscopy was valuable in diagnosing endobronchial TB in children and in discovering reasons for inadequate treatment response.
Terbinafine Oral Granules for Children with Tinea Capitis
Dermatology
Summary and Comment
Free
A welcome addition to therapies for this infection
By Mary Wu Chang, MD
September 12, 2008
Covering:
Elewski BE et al., J Am Acad Dermatol 2008 Jul; 59:41
A Little Hand Hygiene Goes a Long Way
Meta-analysis results of community-based intervention studies indicate that use of <$EMPH_O>non<$EMPH_C>antibacterial soap and hand-hygiene education significantly reduce respiratory and GI illnesses.
How Common Is Herpes Infection in Hospitalized Neonates?
Infectious Diseases
Summary and Comment
Herpes simplex infection is rare in hospitalized neonates, but the presence of certain clues should prompt suspicion.
By Robert S. Baltimore, MD
August 27, 2008
Covering:
Caviness AC et al., J Pediatr 2008 Aug; 153:164
Kimberlin DW., J Pediatr 2008 Aug; 153:155
Long SS., J Pediatr 2008 Aug; 153:157